30 European Projects Found
Searched on 125080 European Projects
FINISHED
A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients (MERCURIC)
Start date: Dec 1, 2013, End date: Nov 30, 2020,
Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less than 5% because of ineffective treatments. Increased understanding of cancer biology, coupled with the implementation of “omi ...
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13
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Methods in Research on Research (MIROR)
Start date: Mar 1, 2016, End date: Feb 29, 2020,
Our aim is to create, in Europe, an innovative and ambitious multidisciplinary intersectoral joint doctoral training programme, dedicated to Methods in Research on Research (MIROR) in the field of clinical research. “Research on Research”, is an emerging new scientific discipline that aims to reduce waste in research and increase research value. Waste in research represents tens of billions of Eur ...
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7
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Paediatric Inflammatory Bowel Diseases Network for Safety, Efficacy, Treatment and Quality improvement of care (PIBD-SETQuality)
Start date: Jan 1, 2016, End date: Dec 31, 2019,
"The incidence of paediatric onset Inflammatory Bowel Diseases (PIBD) has risen dramatically in recent decades. Compared to adult forms, PIBD reflects a more severe disease, more often requiring aggressive treatment with immunomodulators, and thereby exposing children to a life-long risk of serious disease and treatment-related adverse events, such as infections and malignancies. Therefore, there ...
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12
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Infectious Diseases teaching Europe/Africa Learning
Start date: Sep 1, 2016, End date: Aug 31, 2019,
... an interactive web interface.Deliverables will be split in 3 work packages: WP1 =I3DC: International Intensive Infectious Disease Course for European Students delivered over a week for students of Paris Descartes University, Edinburgh Medical University, University of Antwerpen and University of the Sacred Heart of Roma. This curriculum was implemented 3 years ago successfully in Paris, Roma and ...
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6
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Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies (SPRINTT)
Start date: Jul 1, 2014, End date: Jun 30, 2019,
The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from the expansion of an older population with specific medical needs related to multiple chronic disorders. As a consequence, the medical conditions of a large and growing seg ...
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27
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Doing It Together science (DITOs) (DITOs)
Start date: Jun 1, 2016, End date: May 31, 2019,
...policies.The proposal includes the participation of policy bodies (European Citizen Science Association, DE), SMEs (Tekiu, UK; Eutema, AT), Universities (University College London, UK; Universite Paris Descartes, FR; University of Genève, CH), Science galleries and public spaces (Royal Belgian Institute of Natural Sciences, BE; Medialab-Prado, E; Kersnikova Institution, SL) and NGOs (Meritum Assoc ...
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11
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Health and Environment-wide Associations based on Large population Surveys (HEALS)
Start date: Oct 1, 2013, End date: Sep 30, 2018,
Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th ...
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37
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QUANTItative scanning probe microscopy techniques for HEAT transfer management in nanomaterials and nanodevices (QUANTIHEAT)
Start date: Dec 1, 2013, End date: Nov 30, 2017,
The thermal properties of nanostructured materials are of fundamental importance to modern technology, but at present reproducible metrological definitions, tools and methods do not exist. This is because the mechanisms of heat transport at the nanoscale are entirely different to those at the macro scale.The project will place nanothermal metrology on a solid basis by an integrated physics-based e ...
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23
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Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified (CFMATTERS)
Start date: Oct 1, 2013, End date: Jun 30, 2017,
Antimicrobial resistance is arguably the most significant challenge facing the EU health care system. The unnecessary use of antibiotics is a key driver in the development of antibiotic resistance. Cystic Fibrosis (CF) represents a unique disease model to study bacterial resistance and to explore therapeutic strategies for same, as chronic lung infection overlaps with acute lung exacerbations caus ...
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15
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Open Project for the European Radiation Research Area (OPERRA)
Start date: Jun 1, 2013, End date: May 31, 2017,
"Within the OPERRA project, it is proposed that the MELODI Association, as a well-advanced network, takes the lead in establishing the necessary structures able to manage the long-term European research programmes in radiation protection, also taking advantage of the valuable experience gathered through the DoReMi network of excellence. Whilst in fields adjacent to low-dose risk research (radioeco ...
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71
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Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)
Start date: Mar 1, 2012, End date: Feb 28, 2017,
The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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32
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"Perceptual Representation of Illumination, Shape and Material" (PRISM)
Start date: Jan 1, 2013, End date: Dec 31, 2016,
"Visual perception provides us with a richly detailed representation of the surrounding world, enabling us to make subtle judgements of 1) 3D shape, 2) the material properties of objects, and 3) the flow of illumination within a scene. Together, these three factors determine the intensity of a surface in the image. Estimating scene properties is crucial for guiding action and making decisions like ...
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10
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Spatial Cognition (SpaceCog)
Start date: Mar 1, 2013, End date: Feb 29, 2016,
Humanoid robots will become important machines to support mankind if they develop similar capabilities as humans have. One of those capabilities is to orient in space and to extract the relevant information from its environment. A common approach has been to build a spatiotopic map of the external world, so called an internal world model. However, since the sensors, such as the eyes (cameras) are ...
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6
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Governance of REsponsible innovATion (GREAT)
Start date: Feb 1, 2013, End date: Jan 31, 2016,
The GREAT project will develop an empirically based and theoretically sound model of the role of responsible research and innovation governance. The project will explore the dynamics of participation in research and innovation, and investigate the characteristics of responsible practices. It will investigate the nature of new partnerships among various stakeholders, researchers and policymakers th ...
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13
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To decipher the optimal management of systemic sclerosis (DESSCIPHER)
Start date: Dec 1, 2012, End date: Nov 30, 2015,
The current approach to diagnosis and management of the rare disease systemic sclerosis (SSc) is based on American College of Rheumatology criteria with low sensitivity and few validated recommendations for the therapy of the disease and its manifold organ manifestations. To overcome these shortcomings, the DeSScipher project will use the multinational, prospective and open EUSTAR (Scleroderma Tri ...
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15
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TRANSLATIONAL RESEARCH AND PATIENT SAFETY IN EUROPE (TRANSFoRm)
Start date: Mar 1, 2010, End date: Nov 30, 2015,
TRANSFoRm will develop rigorous, generic methods for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via:1.\tRich capture of clinical data, including symptoms and signs rather than just a single diagnosis. A generic, dynamic interface, integrated with electronic health records (EHR), will facilitate both diagnostic decision support ...
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25
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Apoptosis Modelling for Treatment Decisions in Colorectal Cancer (APO-DECIDE)
Start date: Nov 1, 2012, End date: Oct 31, 2014,
"With the arrival of new colorectal cancer (CRC) therapeutics targeting specific cell signalling pathways, such as anti-EGFR therapy, personalised cancer treatment is at the door step of clinical practise. This progress in drug development contrasts strikingly with current clinical practice, where decision making depends largely on clinical factors such as tumour staging and age of patient, with t ...
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7
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Overcome failure to Publish nEgative fiNdings (OPEN)
Start date: Nov 1, 2011, End date: Oct 31, 2013,
Full information about completed and ongoing clinical trials is the indispensable base for decision making about medical therapies and diagnostic procedures by patients and doctors. Equally, researchers and research organisations, ethics boards, governments and health system agencies, courts for social justice, pharmaceutical companies and all professional groups of the health care system are depe ...
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11
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Therapeutic challenge in Leukodystrophies: Translational and ethical research towards clinical trials (LEUKOTREAT)
Start date: Mar 1, 2010, End date: Aug 31, 2013,
Leukodystrophies (LDs) are inherited rare neurodegenerative diseases of the white matter and its main component, the myelin, that are affecting predominantly children. Severity of the disease is related to the axonal dysfunction due to myelin deficiency or destruction. Despite the achievement of remarkable advances made in the past decade, there is no current curative therapy. The development of t ...
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25
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Multi-level patient-specific artery and atherogenesis model\nfor outcome prediction, decision support treatment, and\nvirtual hand-on training (ARTreat)
Start date: Sep 1, 2008, End date: Aug 31, 2013,
ARTreat targets at providing a patient-specific computational model of the cardiovascular system, used to improve the quality of prediction for the atherosclerosis progression and propagation into life-threatening events that need to be treated accordingly. ARTreat will provide a three-level patient model describing the 3d arterial tree anatomy, the patient-specific blood flow and blood particle d ...
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23
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Natural Products and related Redox Catalysts: Basic Research and Applications in Medicine and Agriculture (Red Cat)
Start date: Dec 1, 2008, End date: Nov 30, 2012,
Intracellular redox processes are pivotal for cell survival and proliferation. Redox active natural products, enzymes and their mimics may therefore be considered as regulators of various cellular processes which may, for instance, control inflammatory processes, cancer formation and proliferation, but also bacterial, fungal and microbial growth. It is now apparent that redox control exerted by su ...
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10
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European Network for Cell Imaging and Tracking Expertise (ENCITE)
Start date: Jun 1, 2008, End date: Nov 30, 2012,
"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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30
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Initial Training Network: Lateralized Attention Networks (ITN-LAN)
Start date: Sep 1, 2008, End date: Aug 31, 2012,
"The proposed Initial Training Network for Lateralized Attention Networks (ITN-LAN) brings together 6 research teams with established international reputations and, more importantly, is founded on well established collaborations. The long-term scientific objectives of the proposed ITN-LAN are: (1) To validate and standardize a behavioural battery for assessing the attentional networks of the two ...
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7
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Next Generation HIV-1 Immunogens inducing broadly reactive Neutralising antibodies (NGIN)
Start date: Feb 1, 2008, End date: Jul 31, 2012,
"The elicitation of broadly neutralising antibodies (Nab) remains the primary and most challenging goal in HIV-1 vaccine development. Although a few anti-HIV-1 monoclonal antibodies with broadly neutralising capability have been isolated from infected individuals, none of the immunization strategies thus far explored has proven effective in inducing similar antibodies. Objective of this applicatio ...
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18
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Enhancing biomorphic agility through variable stiffness (STIFF)
Start date: Jan 1, 2009, End date: Dec 31, 2011,
Description
Endowing a highly biomimetic robot hand-arm system with the agility, robustness and versatility of the human motor system
The goal of STiFF is to equip a highly biomimetic robot hand-arm system with the agility, robustness and versatility that are hallmarks of the human motor system by ...
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7
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Developing Medical Genetics Education through Curriculum Reforms and Establishment of Postgraduate Training Programs (MedGen)
Start date: Dec 1, 2013,
Armenia and Israel are countries with high prevalence of genetic disorders. However, health care systems in these countries have not responded appropriately to the rising needs of genetic services. Although in both countries medical profession and public health officials consider genetic conditions as a priority, there is a scarcity of workforce trained in clinical genetics, genetic counseling and ...
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10
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European Molecular Imaging Doctoral School
Start date: Oct 1, 2011,
Molecular imaging is a developing technology that allows for the study of molecular and cellular events in living subjects (human and animal). This field of research is rapidly growing in industry and academia and requires the expertise of PhD level molecular imaging professionals. This type of professional should have an in depth theoretical understanding of the different scientific domains withi ...
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7
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EUROPLAT European Network for Psychology Learning & Teaching
Start date: Oct 1, 2009,
The psychological sciences have relevance to all EU citizens. They provide an understanding of human behaviour in society, the workplace, educational settings and the home. There is a need to enhance the quality of education within the psychological sciences in order to increase the impact of these psychological sciences to meet the Lisbon goals and the education of lifelong learners that are inst ...
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32
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PREDIL’s central concern is on the harmonization of societal needs and pedagogicalpractices.The project intends to map (via a discursive approach) current teaching practices ontopupils’ preferences with regard to ICT applications in the curriculum and to developsupport tools for teachers. Semi- structured interviews, focus group discussions,structured discussion fora and on-line data collection me ...
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7
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The Cyberlab project will provide laboratory training between different sites in Europe using video-conferencing techniques. As advanced laboratory equipment is expensive and accessible only to a select group of students/trainees, and as travel to and research at specialist laboratories is both expensive and time-consuming, the Cyberlab project addresses a real need for distance laboratory trainin ...
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