Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)

Start date: Jan 1, 2016, End date: Dec 31, 2021,

The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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 43

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Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip (ChipScope)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. ...
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 7

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Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
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European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry (EN_ACTI2NG)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors an ...
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 11

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The artificial pancreas in children aged 1 to 7 years with type 1 diabetes (KidsAP)

Start date: Jan 1, 2017, End date: Jun 30, 2020,

TYPE 1 DIABETES is one of the most COMMON CHRONIC diseases in children with a RAPID increase in number of cases particularly in young children. Type 1 diabetes is associated with LIFE-LONG dependency on insulin administration. POOR glucose control leads to diabetes COMPLICATIONS, e.g. eye, heart, kidney disease, including BRAIN changes in young children. Episodes of VERY LOW glucose levels may be ...
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 14

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Autologous Stem Cell Seeded Tissue Engineered Trachea (TETRA)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

CLINICAL PROBLEM AND UNMET NEEDThere are 11,827 patients with severe structural airway disease in Europe. Even with the current standard of care, when hospitalised this group of patients has a 22% risk of dying. Patients are currently subjected to repeated surgical interventions (stent insertion) which have a high failure rate. Other therapeutic strategies under development include synthetic trac ...
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 14

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Integrating Technology into Mental Health Care Delivery in Europe (ICare)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

The evidence base of Internet-based interventions in the prevention and treatment of mental health conditions has rapidly grown in the past decade. Yet many European countries (e.g., Germany, Austria, Switzerland, Great Britain, The Netherlands, Spain) have not implemented these promising approaches into health systems. Individuals with risk conditions or distinct mental health problems interested ...
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 13

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A drug strategy targeting stabilised mutant p53 to fight metastatic platinum-resistant ovarian cancer (GANNET53)

Start date: Oct 1, 2013, End date: Mar 31, 2019,

"Epithelial ovarian cancer (EOC) is the most lethal gyncaecological malignancy causing 41900 deaths annually in Europe. The predominance of aggressive Type II tumours, which are characterised by a high frequency of p53 mutations, and primary or acquired resistance to platinum-based chemotherapy profoundly contribute to the high mortality rate. With current standard therapy the median overall survi ...
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 20

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Protecting the health of Europeans by improving methods for the detection of pathogens in drinking water and water used in food preparation (Aquavalens)

Start date: Feb 1, 2013, End date: Jan 31, 2018,

The AQUAVALENS consortium has brought together SMEs, Industries, Universities and Research Institutes with the mission of protecting the health of European Citizens from contaminated drinking water and water used in food processing. We will achieve this by developing sustainable technologies to enable water system managers whether in large or small water systems or within food growers or manufactu ...
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 43

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European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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 48

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Advances in Small Trials dEsign for Regulatory Innovation and eXcellence (ASTERIX)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

"ASTERIX will contribute towards the expected impact listed in the work program by delivering validated innovative statistical design methodologies for cost efficient clinical trials deriving reliable results from trials in small population groups, especially focusing on rare diseases. It directly addresses the rights of the estimated 30 million European patients suffering from rare diseases to th ...
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 7

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TOWARDS SAFE AND EFFECTIVE IMMUNOTHERAPY OF PERSISTENT LIFE-THREATENING FOOD ALLERGIES (FAST)

Start date: Sep 1, 2008, End date: May 31, 2017,

The FAST project aims at the development of safe and effective treatment of food allergies. It targets persistent and severe allergy to fish and fruit. Besides persistence and severity, this choice is based on prevalence and the importance of these foods for a healthy diet. Classical allergen-specific immunotherapy (SIT) for treatment of food allergy using subcutaneous injections with food extract ...
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 19

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Foundational Research on MULTIlevel comPLEX networks and systems (MULTIPLEX)

Start date: Nov 1, 2012, End date: Oct 31, 2016,

Future advancements in ICT domain are closely linked to the understanding about how multi-level complex systems function. Indeed, multi-level dependencies may amplify cascade failures or make more sudden the collapse of the entire system. Recent large-scale blackouts resulting from cascades in the power-grid coupled to the control communication system witness this point very clearly. A better unde ...
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 24

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European Medicines Research Training Network (EMTRAIN)

Start date: Oct 1, 2009, End date: Sep 30, 2016,

...signed to foster industry/academia mobility and collaboration.The public Consortium is made up of the six pan-European biomedical science (BMS)research infrastructures from the ESFRI roadmap, and the Medizinische Universitaet Wienas managing entity. The six ESFRI-BMS research infrastructures cover a broad spectrum ofcompetences from molecules to humans: structural biology (Instruct), bioinformatic ...
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Development of a late-onset-Alzheimer’s disease (LOAD) profile for accurate diagnosis and identification of potential therapeutic approaches (LOAD Profile)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that currently affects 2% of the population in industrialized countries; the risk of LOAD increases in individuals beyond the age of 70 and it is predicted that the incidence of LOAD will increase 4-fold within the next 50 years which may cause a great socioeconomic problem. Early diagnosis and evidence-based interventions that ...
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 5

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Improving HSCT By Validation Of Biomarkers & Development Of Novel Cellular Therapies (CELLEUROPE)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

Novel transplant regimens are currently being developed to improve beneficial GvL effects and reduce GvHD and infections via several new forms of cellular therapies. This newly emerging supra-disciplinary field of cellular therapy and regenerative medicine is also being used to improve outcomes in autoimmune disease (such as Rheumatoid Arthritis) and cancers. The goal of this research programme is ...
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 13

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Natural Killer Cell-Based Anti-Cancer Immunotherapies: Research training in molecular medicine and biotechnology business (NATURIMMUN)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

"In the research part we will deal with the basic principles of the innate immune defense used to control tumors and viral infections with a focus on NK and NK/T cells, including analysis of NK receptor genomics/epigenetics, gene polymorphisms/disease linkage, differentiation of hitherto unrecognized NK cell subpopulations and novel ligands for NK receptors exposed by tumor and/or virally infected ...
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 12

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A Gateway to European Kidney Research Resources - KidneyConnect (KidneyConnect)

Start date: Aug 1, 2013, End date: Jul 31, 2016,

Diabetes, Cardiovascular and Chronic kidney (DCC) -diseases are relentlessly increasing globally, causing enormous human suffering, premature deaths and unsustainable costs. Leading European research has indisputably pointed that the kidney filtration barrier and its epithelial cell, the podocyte, is a common denominator for the DCC-diseases. However, European excellence and expertise have remaine ...
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 19

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Vitamin D And LIfestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention (DALI)

Start date: Mar 1, 2010, End date: Dec 31, 2015,

Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
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 18

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Manual Operation for 4th Generation Airliners (Man4Gen)

Start date: Sep 1, 2012, End date: Dec 31, 2015,

The project will identify current deficiencies of situational awareness and manual control of modern flight decks, and impact the design of procedures, training and cockpit design in the aerospace industry. Procedures will be developed to help the pilot identify not only the fault, but where the airplane is with respect to its operational envelope and limits. By empowering the pilot to utilize his ...
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 10

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Novel biomimetic strategy for bone regeneration (INNOVABONE)

Start date: Nov 1, 2011, End date: Oct 31, 2015,

The importance of developing novel approaches for bone repair is underscored by the heavy burden on health care costs and patient suffering caused by traumatic, osteoporotic and osteolytic metastatic bone lesions. To address these health challenges, we will develop optimally performing bioinspired biomaterials mimicking the natural physiological processes underlying bone repair. Our overall approa ...
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 14

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multi-LAyer SpAtiotemporal Generalized NEtworks (LASAGNE)

Start date: Nov 1, 2012, End date: Oct 31, 2015,

Thanks to modern ICT, a new generation of large data sets of social, biological, and man-made systems are now available. Many more will be produced at an ever–increasing rate in the near future. Such data contain high precision and integrated information on the nature and the evolution -in space and time- of the state of each single component, together with information on different types of intera ...
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 8

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bioMARkers and molecular tumor classification for non-genotoxic CARcinogenesis (MARCAR)

Start date: Jan 1, 2010, End date: Jun 30, 2015,

MARCAR aims to establish reliable early markers and molecular classification of tumors in non genotoxic carcinogenesis, applying a mechanism-based approach. Benefits are improved drug safety, more efficient drug development, and progress with 3 R issues. MARCAR focuses on rodent liver, the major target organ of non-genotoxic carcinogens (NGC). However, this approach will facilitate predictions for ...
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 12

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Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)

Start date: Jan 1, 2010, End date: Dec 31, 2014,

Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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 30

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ROLE OF ANTISENSE RNAs ON PU.1 REGULATION AND HEMATOPOIESIS (PU.1 Antisense)

Start date: Jan 1, 2012, End date: Dec 31, 2014,

PU.1 levels are critical for normal hematopoiesis and, even modest alterations can lead to leukemia and lymphoma. To achieve optimal expression of the PU.1 gene at different stages of hematopoiesis, multiple interactions are required between its regulatory elements to form fine chromatin architecture. While significant advances have been made in understanding which PU.1 locus chromatin states are ...
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 2

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Gaining sage on the Epoetins' saga: assessing long term risks and advancing towards better Epoetin driven treatment modalities (EPOCAN)

Start date: Oct 1, 2011, End date: Sep 30, 2014,

EpoCan aims to develop and implement a comprehensive interdisciplinary strategy to assess the long-term risks of erythropoietin (EPO) and its derivatives (epoetins) on tumour growth progression and thromboembolic events in cancer patients, cardiovascular events, and the development of cancer in chronic kidney disease. Approximately 400,000 patients across Europe receive epoetins treatment each yea ...
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 13

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Fatty liver: Inhibition of Progression (FLIP)

Start date: Jan 1, 2010, End date: Jun 30, 2013,

"Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practising hepatogastroenterologist due to the obesity epidemic and its potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. The aim of the FLIP (Fatty Liver: Inhibition of Progression) project is to understand and prevent the progression of liver dis ...
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 17

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The impact of Regulation (EC) No 1394/2007 on the development of Advanced Therapy Medicinal Products (ATMPs): an academic perspective (Academic GMP)

Start date: Sep 1, 2010, End date: May 31, 2013,

Advanced Therapy Medicinal Products (ATMPs) are medicinal products for human use, based on gene therapy, somatic cell therapy or tissue engineering. A rapidly growing area in translational research, they represent the ‘next generation’ of complex medicines for complex diseases and pose particular challenges to medicines regulation.Regulation (EC) No 1394/2007 has been designed to ensure the free m ...
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 9

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Mobilität im Alter (MOBIL)

Start date: May 31, 2008, End date: May 30, 2013,

Wenn Menschen altern, verlieren die Muskeln an Kraft und die Bewegungen verlangsamen sich. Dies erhöht das Verletzungsrisiko durch Stürze und macht abhängig von Hilfsmitteln und Unterstützung im täglichen Leben. MOBIL ist ein grenzüberschreitendes Forschungsprojekt zur Entwicklung neuer Verfahren und deren Kombination bzw. neuer Geräte die die Mobilität im Alter bewahren bzw. verbessern.Ziele:• Da ...
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 3

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Nanoelectronics for Mobile AAL Systems (MAS)

Start date: Apr 1, 2010, End date: Mar 1, 2013,

The ENIAC JU project MAS is developing nanoelectronics components for applications in the field of health and wellness, and to create a development platform for the design of complete flexible, robust and safe mobile ambient-assisted-living systems. The project covers remote patient supervision using multi- parameter biosensors and telecommunications networks to improve the quality of the clinical ...
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Einfluss von pflanzlichen Lebensmitteln auf Folgeerkrankungen von Typ-2 Diabetikern (DIAPLANT- Diabetes and plant food products)

Start date: Jun 30, 2009, End date: Dec 30, 2012,

Diabetes wird als eine der großen Herausforderungen für die öffentlichen Gesundheitssysteme gesehen. Sowohl Wien als auch die Region Bratislava zeigen eine hohe Anzahl an Neuerkrankungen an Diabetes. (In den Großstädten ist dieser Wert der Diabeteserkrankungen signifikant höher als in ländlichen Gebieten). Ein wichtiger Risikofaktor für Diabetes ist die Ernährung. Das Projekt DIAPLANT erforscht, w ...
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 2

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Neurotransmitter Cys-loop receptors: structure, function and disease (NeuroCypres)

Start date: Feb 1, 2008, End date: Jul 31, 2012,

Cys-loop receptors (CLRs) form a superfamily of structurally related neurotransmitter-gated ion channels, comprising nicotinic acetylcholine, glycine, GABA-A/C and serotonin (5HT3) receptors, crucial to function of the peripheral and central nervous system. CLRs cover a wide spectrum of functions, ranging from muscle contraction to cognitive functions. CLR (mal)function is linked to various disord ...
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 24

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Umweltschadstoffe in Mutter-Kind-Paaren: Belastungssituation im Raum Bratislava-Wien (UM-MUKI)

Start date: Aug 31, 2009, End date: Apr 30, 2012,

Umweltschadstoffe können Gesundheitsschäden hervorrufen. Derzeit gibt es nur vereinzelt Studien über die Gesundheitsbelastung bestimmter Umweltschadstoffe. Das vorliegende Projekt setzt bei den Neugeborenen als der empfindlichsten Bevölkerungsgruppe an und entwickelt längerfristige Präventivmaßnahmen zur Verringerung umweltbedingter gesundheitlicher Beeinträchtigungen.Ziele:• Nach Vorliegen von Er ...
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 3

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Genetische Faktoren bei der rheumatoiden Arthritis in Österreich und der Slowakischen Republik (RASGENAS)

Start date: Feb 28, 2009, End date: Feb 29, 2012,

Die Slowakische Republik und Österreich haben gleiche klimatische Bedingungen, die Bevölkerung war jedoch aufgrund ihrer Geschichte jahrzehntelang durch den Eisernen Vorhang getrennt. Diese Situation ist ideal für eine Forschung nach genetischen Ursachen der rheumatoiden Arthritis. Hierfür ist eine große Zahl an Versuchspersonen erforderlich, die im Raum Wien – Bratislava vorhanden ist. Dieser Ums ...
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 2

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ASSESSMENT OF HEARING IN THE ELDERLY: AGING AND DEGENERATION - INTEGRATION THROUGH IMMEDIATE INTERVENTION (AHEAD III)

Start date: May 1, 2008, End date: Oct 31, 2011,

"Hearing loss is one of the most common chronic health conditions in the elderly population with important implications for patient quality of life. The diminished ability to hear and to communicate is frustrating in and of itself, but the strong association of hearing loss with depression and functional decline adds further to the burden on individuals who are hearing impaired. Hearing loss can ...
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 19

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European IPF Network: Natural course, Pathomechanisms and Novel Treatment Options in Idiopathic Pulmonary Fibrosis (eurIPFnet)

Start date: Jan 1, 2008, End date: Jun 30, 2011,

In the eurIPFnet consortium, leading European basic and clinical scientists in the field of interstitial lung diseases associate to jointly decipher the natural course and molecular pathomechanisms of Idiopathic Pulmonary Fibrosis (IPF) and to develop new therapeutic strategies for patients with IPF. This devastating disease affects about 360.000 patients in the EU and causes a substantial socioec ...
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 13

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Vienna Biocenter European Researchers Night (VBC ERN)

Start date: May 1, 2009, End date: Nov 30, 2009,

"Science is central to the success of the European society and to tackle some of the major problems mankind is facing in the near future. Nevertheless, negative stereotypes about scientists persist. While a slow erosion of these stereotypes is detectable, continued and sustained efforts are necessary to overcome this prevalent barrier to increase the number of scientists in Europe. The most effici ...
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 7

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Monitoring and Minimisation of Traffic-Induced Noise and Air Pollution Along Major Alpine Transport Routes (ALPNAP)

Start date: Dec 31, 2004, End date: Dec 30, 2007,

A network of regional experts aims at the integrated use of advanced science-based methods to monitor, assess, and predict air pollution and noise and their impact on the environment, quality of life and health along major transport routes. These methods are adapted to the Alpine topography and its specific meteorological phenomena which often amplify the levels of concentration and noise. The pur ...
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 11

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Anatomical Models in European Perspective

Start date: May 1, 2012,

The European Union is a patchwork of nations and cultures. From the outside it seems like there is hardly any recognizable pattern to identify, but an insider’s view will reveal interesting lines along which European citizens are connected to each other. Along these lines one could see that the countries of the EU are indeed united in diversity. One of those intangible but visible patterns form th ...
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 3

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EUROPALS - European Pathology Assessment & Learning System

Pathology is a medical specialty that provides the histological (microscopical) diagnoses in clinical settings. Every diagnosis is made by the pathologist himself after microscopic examination of the cells and tissues that are removed from a patient, and this diagnosis is the golden standard for further decisions on treatment and prognosis. At this moment (and in the foreseeable future) there is n ...
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