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Over 40 European Projects Found

Searched on 125080 European Projects

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"There is now overwhelming evidence that glycosylation changes during the development and progression of various malignancies. Altered glycosylation has been implicated in cancer, immune deficiencies, neurodegenerative diseases, hereditary disorders and cardiovascular diseases. Currently, antibodies are playing a central role in enabling the detection of glycoprotein biomarkers using a variety of ...
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"The project will investigate pragmatic and epistemic benefits of delusional beliefs, distorted memories and confabulatory explanations in the context of normal and abnormal cognition. The notion of ""epistemic innocence"" will be developed to capture an unexplored phenomenon, the existence of cognitions whose overall epistemic benefits, in terms of enabling the acquisition or preservation of know ...
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Mitochondria as regulators of fungal virulence (MitoFun)

Start date: Mar 1, 2014, End date: Feb 28, 2019,

Fungal diseases represent a significant and growing threat to human health, particularly since the AIDS pandemic and increasing use of immunosuppressive drugs has produced a massive population of people with impaired immunity who are vulnerable to fungal infections. A great challenge in medical mycology is to understand how fungal virulence evolves. The vast majority of fungal species are not hum ...
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Precision Lepton Flavour Conservation Tests in Kaon Decays (KaonLepton)

Start date: Jan 1, 2014, End date: Dec 31, 2018,

"A unique and innovative test of a cornerstone principle of the Standard Model of particle physics, the Lepton Favour (LF) conservation, is proposed in the framework of the NA62 experiment at CERN. The search for nine decay modes of the charged kaon and the neutral pion forbidden in the Standard Model by LF conservation will be carried out at a record sensitivity of one part in a trillion. Such se ...
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Asymptotic Graph Properties (APGRAPH)

Start date: Dec 1, 2012, End date: Nov 30, 2018,

Many parts of Graph Theory have witnessed a huge growth over the last years, partly because of their relation to Theoretical Computer Science and Statistical Physics. These connections arise because graphs can be used to model many diverse structures.The focus of this proposal is on asymptotic results, i.e. the graphs under consideration are large. This often unveils patterns and connections which ...
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Analysis of Natural Language for Real World Applications (ANALYSIS)

Start date: Sep 1, 2013, End date: Aug 31, 2018,

Natural language understanding, information extraction, and machine translation are critical for human-machine interaction and key technologies in many everyday applications (e.g. search engines, mobile devices, robots). Natural language understanding systems transform spoken language or written texts into syntactic and semantic structures. Critically, these systems need to be able to work flexibl ...
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Nanotechnology is a rapidly evolving enabling technology with the potential to revolutionise modern life. However, an increasing body of scientific evidence would suggest that some materials in their nano-form may induce harmful biological or environmental effects through a variety of potential mechanisms, not all of which are fully understood or quantified as yet. A key confounding factor is tha ...
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Apoptosis-induced proliferation (AiP) is a recently discovered biological process that apoptotic cells are able to stimulate neighbouring cells to undergo additional proliferation. Studies in several model organisms including mammals have suggested that AiP is evolutionary conserved, and may have relevance to both tissue regeneration and tumourigenesis. Intriguingly, caspases, the proteases that n ...
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Metamaterials is a new class of materials constructed from artificial atoms with their optical properties often come from the underlying structures instead of the composing materials. They can therefore be flexibly designed to achieve particular optical functions. As a result, extreme functions like invisibility cloaking and subwavelength imaging become possible. Because of this extreme flexibilit ...
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"A central goal of palaeontology and evolutionary biology is to understand the drivers and dynamics of the major evolutionary radiations that have shaped the history of life on Earth and governed the origins of the modern biota. On land, one of the most important evolutionary diversifications was the radiation of archosaurs, which began around 250 million years ago following the greatest mass exti ...
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Rapidly developing markets such as green construction, energy harvesting and storage, advanced materials for aerospace, electronics, medical implants and environmental remediation are potential key application targets for nanomaterials. There, nanotechnology has the potential to make qualitative improvements or indeed even to enable the technology. Impacts range from increased efficiency of energy ...
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Ageing is increasing at an alarming rate. Subsequently morbidities in the elderly account for a tremendous proportion of government health budgets. Ageing is associated with a sub-clinical elevation in inflammatory markers termed inflamm-ageing. The majority of chronic diseases in the elderly have an inflammatory component to them and most are driven by increased inflammation. The requirement for ...
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"Innovative processes with streamlining and improved control will be conducted in FIBRALSPEC, through Unit for Continuous PAN-based Carbon Fiber Pilot Production. Testing of laminates and prepregs production based the new developed carbon fibres followed by manufacturing of laminates/coupons and high-performance filament wound tubes are also foreseen (equipment for delivering precise volumes the m ...
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Civil society and new migrants in superdiverse contexts (SUPERDIVERSITY)

Start date: Apr 13, 2015, End date: Oct 27, 2017,

This project investigates the role of civil society organisations (CSOs) for new migrants in superdiverse contexts. It explores whether CSOs are instrumental in the building of social relations during their settlement process. This social aspect of settlement, also described as social integration, is crucial regarding other aspects of settlement such as access to education, housing and the labour ...
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Transversal Multilinear Harmonic Analysis (TMHA)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

"This proposal consists of two intimately related programmes. The aim of Programme 1 is to make major contributions to the celebrated restriction theory for the Fourier transform and combinatorial problems of Kakeya-type using emerging multilinear techniques. The aim of Programme 2 is to develop a multilinear perspective on a much broader family of curvature-related problems in harmonic analysis, ...
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Design of new Co-Al-W-based alloys (COALWSUPER)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

"New Co-Al-W-base superalloys will become an essential technology for high efficiency energy generation and transportation. As more pressure is placed on currently available single-crystal Ni-based superalloys to perform at even higher temperatures, Co-Al-W-base superalloys are likely to become their replacement in the future. Recent studies have shown that this new class of alloys possesses inter ...
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"The ability to copy others lies at the heart of our capacity to learn languages, social rules and acquire material culture. While imitation is a core feature of human life, understanding how it evolved, how it develops and the role of cultural transmission are not fully understood. Moreover, most of our understanding comes from studies of tool use, while neglecting the role of imitation in other ...
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Graphene Based Active Metamaterials (GraB-A-Meta)

Start date: Mar 1, 2015, End date: Feb 28, 2017,

This proposed Fellowship is aimed at developing active control of optical properties that may not be found in nature by synergising the “graphene metamaterials” technology invented at the applicant’s institute in Korea and the “novel design of metamaterials with unnatural properties” developed by the host university through knowledge sharing and technology transfer by the incoming top-class resear ...
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Scalable ProactivE Event-Driven Decision making (SPEEDD)

Start date: Feb 1, 2014, End date: Jan 31, 2017,

SPEEDD (Scalable ProactivE Event-Driven Decision making) will develop a system for proactive event-based decision-making: decisions will be triggered by forecasting events -whether they correspond to problems or opportunities- instead of reacting to them once they happen. The decisions and actions will be real-time, in the sense that they will be taken under tight time constraints, and require on- ...
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Exploring the Security-Democracy Nexus in the Caucasus (CASCADE)

Start date: Feb 1, 2014, End date: Jan 31, 2017,

CASCADE will:- scrutinise Caucasian states and societies for the root causes of conflict and insecurity, conduct synergetic research on democracy and security in the Caucasus and investigate their interaction,- analyse the links between the region and its wider neighbourhood,- provide forward-looking analysis on regional security and democratisation processes,- and develop a set of proposals on ho ...
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This research investigates the role of religious difference and encounter by focusing on the multi-religious and notably tolerant Yoruba people of southwest Nigeria. Drawing on a large-scale ethnographic survey on the everyday lives of Muslims, Christians and traditionalists as well as field and archival work produced and collected by a Nigerian/UK-based research team under my leadership, the prop ...
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The main objective of the proposed research project is to create knowledge that will further advance the contributions that the third sector and volunteering can make to the socio-economic development of Europe. These unique ‘renewable resources’ for social and economic problem-solving and civic engagement in Europe are needed more than ever at this time of social and economic distress and enormou ...
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Cooperative initiatives in the field of housing are considered increasingly important for fostering social cohesion in European city regions. Nevertheless, the debates on the potential of third sector housing in different EU member states are currently only weakly connected. It is therefore crucial to inform these debates with timely academic research that is accessible to policy makers and practi ...
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Monitoring Intracranial Pressure (MICP)

Start date: Jan 12, 2015, End date: Jan 11, 2017,

"The most common cause of death in neurosurgical patients is raised intracranial pressure and therefore it is essential that accurate monitoring of this pressure is undertaken clinically. Currently there are no non-invasive methods available. The overall aim of this research proposal is to develop a novel method for monitoring intracranial pressure. The overall aim will be achieved by undertaki ...
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Phosphonic Acids: Surface Electrochemistry (PHASE)

Start date: Dec 3, 2014, End date: Dec 2, 2016,

"This project aims to evaluate the effect of phosphonic acid adsorption on metal surfaces. Much is known about the adsorption of these molecules on oxide surfaces but very little is known about their behaviour on metals. The first primary aim is to determine adsorption and phase behaviour quantitatively as a function of surface charge, which will be controlled by varying applied electrical potenti ...
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Environmental wellbeing backed by increasingly severe legislation dictates that pollution and energy consumption by automobiles must be reduced significantly. The outcomes of this project will enable both these imperatives to be achieved simultaneously. The project aim is to establish production lines in Europe that manufacture components for lightweight complex-shaped automobile body structures ...
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Learning analytics, educational data mining, formative assessment, are all recent buzz words in educational research. In principle, the idea is to find theoretical frameworks, models, procedures, and smart tools to collect, aggregate, analyse, reason on and visualize large scale educational data. LEA's BOX aims at (a) making educational assessment and appraisal more goal-oriented, pro-active, and ...
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"This project will develop a new approach to the textual history of the Pauline Epistles by exploring the biblical text of the earliest commentaries in Greek and Latin. Each author's treatment of their source gives insights into their compositional practices, their attitudes to the Bible and the differing versions of the New Testament known to them. Detailed verbal analysis of the quotations will ...
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"Maintaining the oxygen (O2) concentration at an appropriate level is the most important task for the survival of a living organism. Both low level (hypoxia) and high level (hyperoxia) of O2 have deleterious effect on cells. Brain is especially sensitive to O2 change. These induces a variety of alterations in neuronal function, ionic homeostasis and cell morphology. Recording the network and singl ...
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Kon-Tiki gene network for CNS regeneration (KON-TIKIGENET)

Start date: Mar 1, 2014, End date: Jul 30, 2016,

Regeneration after injury occurs in many animals, revealing that cellular and molecular mechanisms regulate normal organ structure, size and shape. The human central nervous system (CNS) does not regenerate upon damage and as a consequence stroke, spinal cord injury, multiple sclerosis and neurodegenerative diseases result in permanent disability. NG2 cells are repair cells in mammals that respond ...
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"Railway maintenance is a costly activity that can be improved by faster inspection of assets. If the speed of inspection of the railhead can be increased the potential cost savings are significant. Current NDT solutions implement hand held devices that effectively scan at walking pace. EMAT devices have been utilised to demonstrate that a non-contact solution that can be mounted to a vehicle is f ...
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There is increasing awareness of the importance of epigenetics in regulating phenotypic properties relevant to the ecology and evolution of all organisms. For ages, the waterflea Daphnia, has served as a model organism for ecological, evolutionary and toxicological studies. The efforts and results from Daphnia investigations recently have been rewarded by the National Institutes of Health adopting ...
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MITOCHONDRIAL STEROIDOGENESIS in the ADRENAL (MISTRAL)

Start date: Apr 14, 2014, End date: Apr 13, 2016,

Steroid hormones to control sex development, metabolism, stress response, blood pressure and body composition. Steroid hormones synthesis and action is conserved across species. The importance of cofactors in the function of steroidogenic enzymes has become apparent during recent years. Data from in vitro research suggests important regulatory capacity of co-factors significantly influencing total ...
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The proposed project is a comprehensive assessment of the evidence for the figure known as the ‘Teacher of Righteousness’ in the Dead Sea Scrolls discovered at Khirbet Qumran. It is the first such study based on the entirety of the corpus which has only recently become completely accessible. The project will construct a model for how the memory of the Teacher operated within the ancient socio-reli ...
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Exploring quantum Aspects of GravitationaL wavE detectors (EAGLE)

Start date: Mar 1, 2014, End date: Feb 29, 2016,

Gravitational-waves, predicted by Einstein's general theory of relativity, will open up a new window into the universe. Directly detecting them and eventually extracting information about astronomical phenomena requires new instruments with extremely high sensitivity, which only became feasible recently. The current paradigm of gravitational-wave detectors uses kilometre-scale laser interferometer ...
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Sulfation pathways in Health and Disease: SUPA-HD (SUPA-HD)

Start date: Mar 1, 2014, End date: Feb 29, 2016,

Sulfated biomolecules are omnipresent in biology. Highly diverse biomolecules are sulfated by an armada of sulfotransferases that depend on provision of active sulfate in the form of 3’-phospho-adenosine-5’-phosphosulfate (PAPS) for action. In humans, PAPS is exclusively provided by the two bifunctional PAPS synthases PAPSS1 and PAPSS2. A growing number of studies report patients with various muta ...
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"ENCCA aims to establish a durable, European Virtual Institute clinical and translational research in childhood and adolescent cancers that will define and implement an integrated research strategy and will facilitate the necessary investigator-driven clinical trials to introduce the new generation of biologically targeted drugs into standard of care for children and adolescents with cancer. This ...
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Quasirandomness in Graphs and Hypergraphs (QRGRAPH)

Start date: Dec 1, 2010, End date: Nov 30, 2015,

A structure is called quasirandom if it has a number of properties that one would expect from a random structure with similar parameters. For instance, a graph is quasirandom if its edges are spread evenly over the vertices. This concept has been remarkably useful in many areas, including Number theory, Graph theory and the design of algorithms.Quasirandomness is a field that is developing very ra ...
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The economic evaluation of end of life care (EconEndLife)

Start date: Apr 1, 2011, End date: Sep 30, 2015,

Making choices about the health care that we provide in society is a fundamental and unavoidable issue. Economic evaluation aids this decision-making by supplying information about costs and benefits of different interventions. For end of life care, however, current evaluative frameworks are inadequate because they focus only on health and only on the patient. Amartya Sen’s capability approach off ...
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Prostate cancer (PC) is the most prevalent non-cutaneous cancer in men and leads to high morbidity and mortality. Disseminated PC is treated by hormonal treatment in order to block intratumoral activation of the androgen receptor (AR) by 5α-dihydrotestosterone (DHT). Despite this treatment, eventually all patients develop castration-resistant disease (CRPC) which is accompanied by poor prognosis. ...
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