Search for European Projects

11 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Heart OMics in AGEing (HOMAGE)

Start date: Feb 1, 2013, End date: Jan 31, 2019,

As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
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 22

 FINISHED 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

 FINISHED 

Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In TYpe 2 diabetic patients with normoalbuminuria (PRIORITY)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

Patients with diabetes are at risk of developing diabetic nephropathy, which will ultimately result in the requirement for renal replacement therapy and is also associated with high cardiovascular morbidity and mortality. Detection of low concentrations of albuminuria in urine (microalbuminuria) is the current clinical standard for detecting those at significant risk and targeting preventive treat ...
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 21

 FINISHED 

Utility of omic-based biomarkers in characterizing older individuals at risk for frailty, its progression to disability and general consequences to health and well-being - The FRAILOMIC Initiative (FRAILOMIC)

Start date: Jan 1, 2013, End date: Dec 31, 2017,

The forecasted increase in the number of older people for this century will be accompanied by an increase of those with disabilities. Disability is usually preceded by a condition named frailty that encompasses changes associated with ageing, life styles and chronic diseases. To detect and intervene on it is of outstanding importance to prevent disability, as recovery from disability is unlikely. ...
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 29

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Translational research (training) in Polycystic Kidney Disease (TranCYST)

Start date: Dec 1, 2012, End date: Nov 30, 2016,

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited kidney disorder with a prevalence of more than 1:1000, characterized by the development of renal cysts, slowly progressing towards end-stage renal disease. ADPKD is often associated with extra-renal complications, which can be devastating. Current therapy is directed towards limiting the morbidity and mortality from these complic ...
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 7

 FINISHED 

Molecular Medicine for Bladder Cancer (BCMolMed)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

BCMolMed integrates complementary and multi-disciplinary expertise of two main (research-intensive SME-academia) and five associate partners with the objective to generate a state of the art training platform on application-oriented biomarker research and systems biology. Special emphasis is placed on the efficient employment of proteomics and bioinformatics techniques to clinical research, and un ...
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 3

 FINISHED 

The role of Chronic DNA damage in Ageing and Age-related pathology (CodeAge)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

Ageing is an inexorable homeostatic failure of largely unknown aetiology that leads to increased vulnerability to disease limiting the quality of life in the elderly and creating high costs to the society. Until recently, the daunting complexity of the ageing process, the conspicuous lack of tools to study it, and a dearth of experimentally tractable model systems have greatly hindered any hypothe ...
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 9

 FINISHED 

Translation of novel Biomarkers for Bladder Cancer for clinical outcome prediction (TransBioBC)

Start date: Sep 1, 2013, End date: Aug 31, 2016,

Currently, clinical diagnosis and monitoring of bladder cancer (BC) relies on invasive, highly costly cystoscopy. Additionally, due to high recurrence rates BC treatment is associated with frequent follow-up of patients, making BC one of the most costly types of cancer in terms of management cost. Thus there is a clear clinical need for the development of new approaches for early detection of recu ...
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 5

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Markers for Sub-Clinical Cardiovascular Risk Assessemnt (EU-MASCARA)

Start date: Dec 1, 2011, End date: May 31, 2016,

EU-MASCARA is a collaborative project that aims to improve diagnosis of cardiovascular diseases and prediction of cardiovascular risk by analysing a panel of biomarkers. EU-MASCARA aims to examine genetic, proteomic and metabolomic markers together with markers of inflammation, oxidative stress and cardiac remodelling to study their incremental diagnostic and predictive value over and above existi ...
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 16

 FINISHED 

Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)

Start date: Jan 1, 2010, End date: Dec 31, 2014,

Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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 30

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IMPROVEMENT OF TOOLS AND PORTABILITY OF MASS SPECTROMETRY-BASED CLINICAL PROTEOMICS AS APPLIED TO CHRONIC KIDNEY DISEASE (PROTOCLIN)

Start date: May 15, 2010, End date: May 14, 2014,

The number of patients with chronic kidney disease (CKD) is increasing steadily due to extended life expectancy, long lasting diabetes and obesity. Early unambiguous detection of patients at risk is both a clinical and scientific challenge. Capillary electrophoresis coupled to mass spectrometry (CE-MS), developed by Mosaiques Diagnostics (MD, SME, Germany), has been shown to be an excellent tool f ...
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 4