Autosomal Dominant Polycystic Kidney Disease (ADPKD) is an inherited kidney disorder with a prevalence of more than 1:1000, characterized by the development of renal cysts, slowly progressing towards end-stage renal disease. ADPKD is often associated with extra-renal complications, which can be devastating. Current therapy is directed towards limiting the morbidity and mortality from these complications, whereas effective specific treatments targeting the renal cystic disease are missing.Translational research using innovative approaches from molecular genetics, basic sciences to clinical applications are necessary to unravel the disease mechanism and to develop interventions, monitoring of cystic renal disease progression and to slow down renal cystic disease.In this context, the aim of TranCYST is to offer a multidisciplinary research training program to young researchers for the identification, characterization, and development of novel treatments in ADPKD, to prepare them to become leading scientists who are able to translate fundamental research questions to the clinic and vice versa,