SYNER-G is research project which has the following main goals: (1) To elaborate appropriate, in the European context, fragility relationships for the vulnerability analysis and loss estimation of all elements at risk, for buildings, building aggregates, utility networks (water, waste water, energy, gas), transportation systems (road, railways, harbors) as well as complex medical care facilities (hospitals) and fire-fighting systems. (2) To develop social and economic vulnerability relationships for quantifying the impact of earthquakes. (3) To develop a unified methodology, and tools, for systemic vulnerability assessment accounting for all components (structural and socio-economic) exposed to seismic hazard, considering interdependencies within a system unit and between systems, in order to capture the increased loss impact due to the interdependencies and the interactions among systems and systems of systems. The methodology and the proposed fragility functions will be validated in selected sites (urban scale) and systems and it will implemented in an appropriate open source and unrestricted access software tool. Guidelines will be prepared and the results and outputs will be disseminated in Europe and world wide with appropriate dissemination schemes. SYNER-G is integrated across different disciplines with an internationally recognized partnership from Europe, USA and Japan. The objectives and the deliverables are focused to the needs of the administration and local authorities, which are responsible for the management of seismic risk, as well as the needs of the construction and insurance industry. URL: http://www.vce.at/SYNER-G