The WiserBAN project will create an ultra-miniature and ultra low-power RF microsystem for wireless Body Area Networks (BAN) targeting primarily wearable and implanted devices for healthcare, biomedical and lifestyle applications.The proposed research concerns the extreme miniaturization of the BAN with primarily the areas of ultra low-power radio SoC (System on Chip), RF and Low-frequency MEMS, miniature reconfigurable antennas, miniaturized SiP (System in Package), sensor signal processing and flexible communication protocols.The WiserBAN microsystem will be 50 times smaller than today's radio modules for Personal Area Networks (PAN) solutions, e.g. Bluetooth, that can simply not be embedded in a variety of tiny implants and wearable applications. WiserBAN will thus enable significant take up by the European SME's and industries in healthcare, bio-medical and lifestyle.WiserBAN will also create a major impact on the quality of life of the European Citizens, in particular for improving the comfort and access to ICT for impaired and disabled people of all ages carrying implants or wearing medical devices, hence reducing the risk of social exclusion.