Continuing the SettingTheStage project organized in 2009, scientists will be called again on stage to celebrate the Researchers’ Night 2010 not only through performing arts (incl. theatre) but also through sports. These media will allow scientists to express themselves, their visions and their work. SettingTheStage II brings back together entities from four major cities across Portugal (North, Centre, South) with the aim of creating multiple spaces where scientists and the public can actively engage in the reality of being a scientist. At the core of the project is a series of arts performances to be specifically produced for RN2010, designed to stimulate reflection, discussion and debate on topics related to researchers and their everyday lives: the power and limits of their research, the impact of their research in society. Researchers and arts performers will work together to produce several performances, aimed at different age groups. In the same way, researchers and the public will share and discuss scientific concepts linked to the sports activities that will be organized during the event. Themes for the activities will be, among others, linked to the celebration of the International Year of Biodiversity and the World Day of the Heart, which will be celebrated at the end of September. Artistic performances and sport activities will be complemented with interactive hands-on activities, from small experiments and demos for youngsters, to speed-dating sessions with scientists, science cafe/bar and visits to museums. Awareness will be achieved through a concerted marketing campaign, bringing together the expertise and resources of all partners involved, including the maintenance/updating of the 2009 project design/image, website and blog. SettingTheStage II brings back together a large number of partners involved in the 2009 edition committed to guarantee a successful action.