The goal of S-CASE is to accelerate the software development lifecycle for cloud services by introducing a new agile prototyping paradigm that automates the process of mapping user requirements to concrete software specifications and generates operational code (RESTful services). S-CASE aspires to support software developers in identifying software requirements and business processes in various formats, including textual (requirements/use case documents), formal (UML diagrams), and visual (images of UML diagrams or storyboards) content. In order to realise this vision, S-CASE employs appropriate multimodal information processing techniques, such as natural language and image processing. S-CASE also aims to provide the appropriate mechanisms for synthesising composite executable workflows of resources (software solutions, services, and devices), both proprietary and open source. To this end, semantic matchmaking and service orchestration techniques will be applied for the dynamic discovery of resources and their composition into operational workflows that match the software developer envisaged requirements in the best possible way. All R&D outcomes will be integrated into the S-CASE realm, a cloud-based platform composed of tools for developers and service providers, open-source software repositories and a discoverable service ecosystem that provides the appropriate resources in the form of RESTful services. Three pilot applications will be developed and deployed in real operational environments by two industrial partners and one SME, in order to validate and evaluate the S-CASE paradigm. The aim of the pilots is to showcase how S-CASE can successfully meet different needs and technology requirements in the three domains of energy, social networks and cloud computing infrastructure. In all pilots, an evaluation procedure will be applied for assessing potential gains with respect to the acceleration of the software development process.