CITYREGIO addresses the problems arising from different paces and accents of economic development between centres and their surrounding areas and the problems of their impact on spatial development. The project analyses the mutual interdependence of centres and their surroundings. It approaches cities and the surrounding districts as a unity as far as regional economic development is concerned. From this perspective traditional administrative areas become obstacles. Issues of economic development, spatial planning, location management, and development of human resources and capacities cannot be adequately addressed by local and regional authorities without close co-operation. CITYREGIO addresses this problem in transnational cooperation with the regions of Linz (Austria), Plzen (Czech Republic) and Leipzig (Germany), which are characterised by a number of similar development issues and by geographical proximity in the central CADSES area. Achievements: The CITYREGIO project has achieved the following results: - Improvement of regional competitiveness through economic cluster development and knowledge, exploitation and strengthening of endogenous potentials (locations, labour forces, human resources, branch competencies), scientifically gained expertise on future location and spatial development factors and on the demands of a knowledge based economy, - Preparation and development of currently missing tools for common intraregional spatial development actions (information system, location pools, support of regional management by one-stop shopping, regionally co-ordinated steps for location development and planning measures for investments), - Set-up of objective-oriented co-operation measures between administrations, firms, planning institutions of cities and surrounding areas as well as between the project regions, - Added value for each region by exchanging knowledge, experiences and regional information as a step for further transnational co-operation.