Inequalities and vulnerable groups’ health, as well as the slow advances to achieve the health- related Millennium Development Goals, are concerns that need to be addressed, notably for low and middle-income countries. While some countries have made advances, these remain unknown to other ones which could still benefit from their experience. Higher collaboration could help but is quite difficult to achieve. The MASCOT project gathers therefore 11 partners from 3 geographical areas (Europe, Latin America & Africa), an advisory board and additional relevant experts to answer this problematic.The work is specifically designed to achieve defined objectives:- to create links between North-South and South-South efforts in addressing maternal and child health and health inequalities (MCH&I) in developing countries- to provide evidence on best practice and policy advice for the development of future public health and health systems interventions.Following a first step of standardisation and quality control procedures, the project will implement mapping activities in individual countries of the 3 regions of interest in order to assess the current situation of MCH inequalities, to identify institutions and research teams performing research in this area, to detect promising projects and research results as well as strategies, programs and policies implemented to tackle MCH inequalities. This will result in recommendations of best practices and policy advice to countries willing to implement actions to improve MCH&I. An important part of the work will also stimulate multi-lateral collaboration and knowledge transfer as a key activity of MASCOT. All along the project, different tools such as meetings, workshops, partnering event, website, and brochures will be used to communicate and promote the exchange between health stakeholders and policy-makers. Ultimately MASCOT should thus allow reducing gaps in health inequalities between and within different regions of the world.