"The whole transport industry has to tackle major world-wide challenges such as combating climate change, sustainable use and management of natural resources and waste, energy saving, reducing CO2 emissions, etc.In this context, Europe has adopted ambitious goals towards 50% more efficient road transport system by 2030 decoupling economical growth with transport development needs, overcoming energy and economic crisis, accelerating catch up with the US and keeping ahead of rapidly developing Asian countries.The technological development of specific parts of the value chain is recognized as potential sources for technological progress with significant economic growth. However, since advanced technologies of each component of the transport-related industry are often based on certain stand-alone paths (e.g. addressing only recycling of old vehicles, or only design and construction of new-ones, not looking at the entire value chain) is challenged by several hurtles, it is critical to develop a more holistic and integrated approach of the entire value chain of this industry.Indeed, only such an approach will enable the whole sector to move up a gear in greening its entire life cycle from conception and construction, via use, end-of-life and deconstruction to waste valorisation.To this end, the S_LIFE project aims at a developing the cooperation between EU world-wide class clusters in order to help them develop new scientific (multi-disciplinary research environment), economic (new business model covering entire value chain) and structural (RTD and new technologies-oriented) coherent greening solutions all along the value chain.S_LIFE project will develop strategies and a Joint action plan to link, mobilize and coordinate regional resources with more focus on this challenge. The project will develop tools to assess the regional research potential, share and disseminate best practices through inter-regional joint programs and suggest appropriate financial support."