Biophotonic applications offer a broad range of innovative solutions, e. g. for the ageing society in industrialised countries, for improved health care in third world countries, for surveilling and safeguarding the environment, and for controlling food and drinking water quality. Such biophotonic solutions may relate to analytics, screening, imaging, therapy or surgery techniques.This ERANET-PLUS on Biophotonics aims to consolidate the respective funding activities in the participating countries and regions and to achieve the best possible exploitation of the resources and the innovative potential of European industry and science.This shall be achieved through a joint call primarily focusing on Biophotonics methods and applications that are translatable into products on the short term. On the one hand, already existing biophotonic technology shall be further developed, refined and combined to the stage of pre-commercial demonstrators which should easily be convertible to commercial products. The pre-commercial demonstrator should be used in application fields with a high societal and/or economic relevance for Europe such as medicine (including veterinary medicine), environment, cosmetics, food and drug quality & safety. On the other hand, seed funding shall be provided to promising application-oriented approaches at an early stage of the value chain. The R&D projects (to be) funded under this joint call are expected to perceptibly contribute to increase the health, well-being and security of the European citizens in the near future.The main activities in the framework of BiophotonicsPlus comprise the preparation of the joint call for proposals, the publication and promotion of the call, the joint evaluation and selection of the proposals and the monitoring of the selected R&D projects.