Climate change experts are increasingly pointing-out the importance of adaptation to anticipated changes. as opposed to waiting until impacts are irreversible. Consequences of climate change on river basins can be potentially catastrophic. The Meuse is a transnational. navigable river. one of the largest in NWE. with a catchment basin incorporating 5 Member States. situated in a densely populated area of NWE. Its discharge fluctuates considerably with seasons: it reached 3100 m3/s in winter 1993 at the Dutch/Walloon border and is only 10-40 m3/s in summers. Classed as a rain-fed river. it has no glacier and little groundwater storage capacity to buffer precipitations. A direct link exists between climate evolutions and changes in high & low-flows. putting at risk the assets of the basin. including major infrastructures. industries. priceless historical and ecological heritage. The aims of AMICE. which unites public authorities. universities & NGOs from 5 NWE regions. are: 1) develop a basin-wide climate adaptation strategy. coordinated transnationally. focused on water discharges and the functions influenced by them. The strategy development will take into account climate scenarios. on-going projects. existing measures and the EU Floods Directive (2007/60/EC). with a particular focus on floods & low-flows. 2) realise a set of measures against low-flows & floods. profitable for the international basin of the Meuse and that can be used by other river basins in NWE. 3) reinforce and widen the partnership between stakeholders of the Meuse basin. and increase the exchange of knowledge and experience on prevention. preparedness and protection against flood & drought risks. 4) engage the local population and stakeholders by improving their understanding of climate change. sustainable development. catchment basin functioning. risk consciousness of water hazards and the sense of belonging to a common river basin. across administrative and language borders. Achievements: Main Outputs and Results are available on the projects website:http://www.amice-project.eu/en/