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Over 40 European Projects Found

Searched on 125080 European Projects

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The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, ...
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Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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NEUTRINOS and DARK MATTER (DM) are the most abundant and also the most elusive building-blocks of nature because of their tenuous couplings to the ordinary matter we are made of. Each particle has a mirror image with identical mass and opposite charge: its antiparticle. What is the essential nature of particles and antiparticles? This is a most fundamental open question in science. The laws of phy ...
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A diverse variety of medical or lifestyle conditions lead to a progressive loss of muscle force by functionally impairing myofibril contractility and causing ultimately myofibril loss. Major underlying risk factors of chronic muscle force loss are ageing, inactive lifestyles, and unbalanced nutrition. Together, these factors are predicted to lead to an endemic incidence of muscle weakness both in ...
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InvisiblesPlus

Start date: Feb 1, 2016, End date: Jan 31, 2020,

NEUTRINOS (Ns) and DARK MATTER (DM) are the most abundant particles in the universe. Their couplings to ordinary matter are so tenuous that they remained undiscovered -invisible- until very recently. N masses and DM constitute the first evidence ever of physics beyond the Standard Model of particle physics. The path to build the New Standard Model must confront the fundamental nature of the partic ...
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The objective of MYOCURE is to develop an innovative gene therapy platform to cure rare hereditary muscle disorders, specifically focusing on myotubular myopathy (MTM) and glycogen storage disorder (GSD) type II. These are attractive diseases for gene therapy since they compromise a diverse family of rare genetic diseases typically caused by single gene defects that often provoke significant morbi ...
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The COSMOS proposal aims to reduce Europe’s dependence on imported coconut and palm kernel oils and fatty acids and castor oil as sources for medium-chain fatty acids (MCFA, C10–C14) and medium-chain polymer building blocks. These are needed by the oleochemical industry for the production of plastics, surfactants, detergents, lubricants, plasticisers and other products. In COSMOS, camelina and cra ...
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Light Field Imaging and Analysis (LIA)

Start date: Jul 1, 2014, End date: Jun 30, 2019,

One of the most fundamental challenges in computer vision is to reliably establish correspondence - how to match a location in one image to its counterpart in another. It lies at the heart of numerous important problems, for example stereo, optical flow, tracking and the reconstruction of scene geometry from several photographs. The most popular approaches to solve these problems are based on the ...
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European Training Network on Antiviral Drug Development (ANTIVIRALS)

Start date: Mar 1, 2015, End date: Feb 28, 2019,

Viral infections are a major cause of disease, mortality and economic losses worldwide. Antiviral therapy is an essential instrument to control virus infections. At present, however, licensed antiviral drugs have been developed only against a limited number of viruses (e.g. HIV, HCV, influenza, herpesviruses). There is a clear and unmet need for antiviral drugs to treat infections with other impor ...
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Allergy is the most prevalent chronic inflammatory disease, having great socio-economic impact. Chronic lifelong dependency on symptomatic drugs is an expensive reality for the vast majority of allergy sufferers. Allergen-specific immunotherapy is the only causal and effective treatment targeting the underlying immune mechanism in a more cost-effective way. Yet, long treatment duration and risk of ...
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The aim of the SEEMLA project is the reliable and sustainable exploitation of biomass from marginal lands (MagL), which are used neither for food nor feed production and are not posing an environmental threat.The main target groups are regional authorities and public or private owners of MagLs, who can provide knowledge on land availability and are responsible for managing these. Furthermore fores ...
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Global demand for minerals is growing rapidly, driven by rapid population growth, urbanisation and an increasingly diverse range of technical applications. Global material supply chains linking the extraction, transport and processing stages of raw materials have become increasingly complex and today involve multiple players and product components. An interactive platform that provides transparenc ...
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The Nizami project concerns the modernization of doctoral education, research and internationalization of HEIs in Azerbaijan. This project intends to answer to the urgent need for Azerbaijan universities to revise the rules and content of organizing doctoral studies within Bologna process documents in terms of their consistency, especially on ensuring science and research provisions in relevance w ...
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Statistical multi-Omics UNDerstanding of Patient Samples (SOUND)

Start date: Sep 1, 2015, End date: Aug 31, 2018,

Bioinformatic analysis is the biggest bottleneck in many genomic medicine projects. Our objective is to enable researchers to dramatically increase statistically informed use of personal multi-omic data in medicine. Soon, multiple types of omic technologies will be applied to 100,000s of patient-derived samples, with the three-stage goal of better understanding disease biology, discovery of new in ...
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Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Start date: Apr 1, 2016, End date: Mar 31, 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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Rydberg Quantum Simulators (RYSQ)

Start date: Mar 1, 2015, End date: Feb 28, 2018,

Quantum Simulators provide new levels of understanding of equilibrium and out-of-equilibrium properties of many-body quantum systems, one of the most challenging problems in physics. The main objective of the RYSQ project is to use Rydberg atoms for quantum simulations, because their outstanding versatility will allow us to perform a great variety of useful quantum simulations, by exploiting diffe ...
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Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
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The multi-disciplinary CUPESSE project carries out a comparative analysis of both the demand and supply side of youth unemployment in eleven Member States of the EU and Associated Countries (i.e. Austria, Czech Republic, Denmark, Germany, Greece, Hungary, Italy, Spain, Switzerland, Turkey, and the United Kingdom). These ten countries represent the main empirical scope of the project, but whenever ...
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 14

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Creating Economic Space for Social Innovation (CRESSI)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

"The CRESSI project will explore the economic underpinnings of social innovation with a particular focus on how policy and practice can enhance the lives of the most marginalized and disempowered citizens in society. Overall, the bid will take an institutionalist view of the key issues exploring the drivers and structures that lead to marginalization and disempowerment and then setting out how int ...
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The ageing of the European population represents a rapidly rising social and economic challenge. Especially cardiovascular morbidity increases with age, but unfortunately, elderly patients are often difficult to diagnose due to confounding factors, leading to uncertainties in clinical decision making with huge impact on patients’ outcomes. Hence, there is an unmet need for novel biomarkers for mor ...
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 22

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Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish th ...
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The Project „From Theory to practice – International Teaching in Field of Archeology” had started from the need identified by us refers to the lack of a coherent learning program at European level in the archaeological field-school for developing students archaeological entrepreneurial abilities. Although the shift towards commercial small-scale entreprises has been identified as the most importa ...
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Neuro-immune alterations in the peripheral and central nervous system play a role in the pathophysiology of chronic pain, and non-coding RNAs (ncRNAs) regulate both immune and neuronal processes. Therefore, ncRNAPain proposes that ncRNAs are critically important master switches for chronic pain.ncRNAPain represents a multidisciplinary consortium of clinical partners, molecular and systems-level n ...
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Gastrointestinal stromal tumours (GIST) are a rare disease that metastasises in up to 85% of patients with subsequent median progression-free survival (PFS) of only around 30 months. Tumours are characterised by activating mutations in the KIT or the PDGFRA gene and therefore treatment is mainly based on tyrosine kinase inhibitors designed to block these mutated receptors. However, drug resistance ...
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"This proposal focuses on the operation of processing units in chemical and biochemical production plants. A new approach, demonstrated recently in the lab and pilot scales as being feasible, is to perform a dynamic online optimization of the plant operating parameters in order to achieve an economically optimal operation while meeting constraints on emissions, product quality and operating limits ...
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The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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The objective of CAP4Access is to develop and pilot-test methods and tools for collectively gathering and sharing spatial information for improving accessibility. The aim is to exploit the power of online maps and mobile devices for fostering awareness of barriers for individuals with limited mobility and for removing such barriers. CAP4Access helps integrating disabled communities into society (s ...
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The Human Brain Project (HBP)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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Mixed-Integer Nonlinear Optimization (MINO)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

"Complex decision making in enterprises should involve mathematical optimization methods, because a “best choice” has to be made out of a huge number of feasible options. A mathematical description of such decision processes typically involves both “continuous” and “discrete” decisions. If the latter are present, the customary modelling approach is to use integer variables, which are also used to ...
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OPTiMiSE (OPtimization of Treatment and Management of Schizophrenia in Europe) will focus on two goals: optimising current treatments in Schizophrenia and explore novel therapeutic options for schizophrenia. The project intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new and experimental interventions. It is expected that the project wi ...
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Sarcomere based Signals in Muscle Remodelling (SARCOSI)

Start date: Apr 1, 2012, End date: Mar 31, 2016,

The sarcomere is the structural unit of striated muscle tissues where thick and thin filaments cooperate to achieve muscle contraction. Recently it is becoming increasingly clear that sarcomeres have in addition to muscle contraction also important signaling functions: Stretch and strain sensing signalosomes are assembled by the giant muscle proteins titin and nebulin, that in turn are embedded in ...
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Europeana network of Ancient Greek and Latin Epigraphy (EAGLE)

Start date: Apr 1, 2013, End date: Mar 31, 2016,

EAGLE is a Best Practice Network that brings together the most prominent European institutions and archives in the field of Classical Latin and Greek epigraphy, to provide Europeana with a comprehensive collection of unique historical sources which constitute a veritable pillar of European culture. In particular, it will supply inscriptions coming from 25 EU countries, providing more than 1.5 M of ...
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"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
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The EXA2GREEN project aims at developing a radically new energy aware computing paradigm and programming methodology for exascale computing. The key aspect of the proposed approach is that the issue of energy consumption and the resulting trade-off with the performance and the accuracy of the overall simulation process will be taken into account in all simulation levels: from the kernel, numerical ...
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LLLight’in’Europe –LifeLong Learning, Innovation, Growth and Human capital Tracks in EuropeAmong all Europeans between 24 and 65 years old who had a tertiary educational degree in 2010, 82.8% were working. In the same age group, 68.3% who completed secondary schooling were working. Only 46% of those who did not complete secondary schooling were working. It is apparent that if Europe wants to be wo ...
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 12

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Optimization of Perennial Grasses for Biomass Production (OPTIMA)

Start date: Oct 1, 2011, End date: Sep 30, 2015,

OPTIMA will integrate an ambitious biology system approach for perennial grasses such as switchgrass, miscanthus and giant reed in the Mediterranean environment. Moreover the perennial species cardoon, which has been proven to be particularly adapted to the Mediterranean climate, will be used as a control species.The main objective of the OPTIMA project is to identify high-yielding perennial grass ...
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Understanding chronic pain and improving its treatment (EUROPAIN)

Start date: Oct 1, 2009, End date: Sep 30, 2015,

We will establish an international team of leading researchers and clinicians (EuroPain) to undertake multidisciplinary translational research which will: 1) increase the understanding of chronic pain mechanisms; 2)facilitate the development of novel analgesic drugs; and 3) improve the treatment of chronic pain patients.Nineteen researchers drawn from the London Pain Consortium, the Danish Pain Re ...
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In the frame of this project it is proposed to define and build a bi-modal PET-US (Positron Emission Tomography and Ultrasound) endoscopic probe combining in a miniaturized system a fully digital, 200ps time resolution Time of Flight PET detector head (TOF-PET) coupled to a commercial ultrasound (US) assisted biopsy endoscope and to launch the first steps of clinical validation.The project address ...
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Les maladies cardio-vasculaires (MCV) et leurs complications sont une des causes principales de mortalité chez lhomme. Ce projet consiste à développer des approches fonctionnelles, afin de définir précisément limpact de plusieurs variants génétiques associés à ces MCV. La meilleure connaissance des gènes liés aux MCV et de leurs mécanismes daction permettrait de développer des approches de prévent ...
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