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Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)
Start date: Dec 1, 2013, End date: Nov 30, 2018,
The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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