6 European Projects Found
Searched on 125080 European Projects
FINISHED
Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)
Start date: Dec 1, 2011, End date: Nov 30, 2015,
The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial ...
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8
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Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)
Start date: Oct 1, 2009, End date: Sep 30, 2015,
RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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42
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Bio-Orthogonal Chemo-Specific Ligation (BioChemLig)
Start date: Oct 1, 2009, End date: Sep 30, 2013,
The Post-genomic era calls for a deep understanding of protein structure and function. The elucidation of protein structures, localization, post-translation modifications, and protein-macromolecule interactions are important to establish their role in the biology of the cell. To establish their role and investigate the protein functions requires the integration of various complementary disciplines ...
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8
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Ankle and Foot Orthotic Personalisation via Rapid Manufacturing (A-FOOTPRINT)
Start date: Oct 1, 2009, End date: Sep 30, 2013,
Disabling foot and ankle pain is common; it impacts negatively on health related quality of life, and it is has major cost implications on health systems across Europe. Foot and ankle orthoses are an effective treatment for these conditions. However, the market is dominated by low cost mass produced products, craftsmanship built customised devices with delivery times >15 days, and a limited ran ...
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13
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A EUROPEAN BIOTECHNOLOGY TRAINING NETWORK FOR THE SUPPORT OF CHEMICAL MANUFACTURING (BIOTRAINS)
Start date: Jul 1, 2009, End date: Jun 30, 2013,
The objective of BIOTRAINS is to deliver a trans-European network of industrially oriented white biotechnologists fully trained in the application of biocatalysis to sustainable chemical manufacturing. Their skills will be developed through a joint research programme at leading national CoE’s (Centre of Excellence) with research projects identified by internationally leading Principal Investigator ...
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13
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Genetic DIversity of AVIdins for Novel Biotech Applications (DIVA)
Start date: Oct 1, 2008, End date: Sep 30, 2011,
"Avidins are amongst the most widely used proteins in biotechnology, with applications encompassing molecular labelling, purification & detection, as well as uses in diagnostics, targeted drug delivery and nanotechnology, such as enantioselective catalysis by artificial catalysts. Avidins also serve as outstanding model systems for our understanding of biomolecular interactions, through their extr ...
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