Search for European Projects

18 European Projects Found

Searched on 125080 European Projects

 FINISHED 

A dedicated trimodality (PET/MR/EEG) imaging tool for schizophrenia (TRIMAGE)

Start date: Dec 1, 2013, End date: Nov 30, 2018,

"Schizophrenia is a severe mental disorder that manifests early in life and imposes a high social and economic burden on European societies. An imaging tool that enables the diagnosis of schizophrenia during early development is extremely desirable and is requested by the clinical community in order to make the management of the disease more effective.TRIMAGE aims to optimise and validate an integ ...
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 11

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Reverse engineering the vertebrate molecular machinery for magnetic biomineralisation (MagnetoGenetics)

Start date: Jan 1, 2013, End date: Dec 31, 2017,

In order to understand distributed biological networks and invent effective molecular therapies, we need to be able to image and control molecular processes across entire live organisms.Although an arsenal of genetically encoded fluorescent sensors and light-activated proteins has recently been developed to visualize and manipulate cellular activity, these methods all suffer from the poor penetrat ...
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 2

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Multimodal Imaging of Neurological Disorders (MINDView)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The key concept behind this proposal is the development of a very high resolution and high efficiency brain dedicated Positron Emission Tomograph (PET) imager that can visualize neurotransmitter pathways and their disruptions in the quest to better diagnose and consequently to better treat schizophrenia. In addition, the plan is for this compact PET imager to be integrated with a Magnetic Resonanc ...
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 10

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Multimodal Molecular Imaging (MUMI)

Start date: Jun 1, 2012, End date: May 31, 2017,

"Imaging has become an integral part of diagnosis and staging of disease. This proposal aims at the development if innovative imaging methods for the visualization and quantitative assessment of biologic processes in-vivo. The simultaneous MR/PET data acquisition will be employed o integrate structural, physiologic and molecular information for the phenotyping of human disease and therapeutic deci ...
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 1

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Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure (OptimEx)

Start date: Oct 1, 2013, End date: Mar 31, 2017,

More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, affecting 10-20% of the elderly and contributing substantially to hospitalizations of elderly HF patients. Currently, no medic ...
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 9

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Anti-Biopharmaceutical Immunization:Prediction and analysis of clinical relevance to minimize the risk (ABIRISK)

Start date: Mar 1, 2012, End date: Feb 28, 2017,

The ABIRISK project provides an integrated approach to the study of immunization against biopharmaceuticals, bringing together a unique panel of experts from different disciplines. ABIRISK will involve many of the European leaders in rheumatology, gastroenterology, hemophilia and multiple sclerosis, caring for ~30,000 patients treated with biopharmaceuticals, with ~10,000 additional patients recru ...
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 39

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Mechanism-Based Integrated Systems for the Prediction of Drug-Induced Liver Injury (MIP-DILI)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The current test systems employed by Industry are poorly predictive for Drug induced liver injury (DILI). The ‘MIP-DILI’ project will address this situation by the development of innovative preclinical test systems which are both mechanism-based and of physiological, pharmacological and pathological relevance to DILI in humans. An iterative, tiered approach with respect to test compounds, test sys ...
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 29

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BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Start date: Feb 1, 2013, End date: Jan 31, 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

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OPtimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) (OPTiMiSE)

Start date: Feb 1, 2010, End date: Jul 31, 2016,

OPTiMiSE (OPtimization of Treatment and Management of Schizophrenia in Europe) will focus on two goals: optimising current treatments in Schizophrenia and explore novel therapeutic options for schizophrenia. The project intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new and experimental interventions. It is expected that the project wi ...
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 25

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Semantic Infostructure interlinking an open source Finite Element tool and libraries with a model repository for the multi-scale Modelling and 3d visualization of the inner-ear (SIFEM)

Start date: Feb 1, 2013, End date: Jan 31, 2016,

The clinical evidence indicates that the number of people with all levels of hearing impairment and hearing loss is rising mainly due to a growing global population and longer life expectancies. Hearing loss caused by pathology in the cochlea or the cochlear nerve is classified as sensorineural hearing loss. The study of the normal function and pathology of the inner ear has unique difficulties as ...
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 11

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Building data bridges between biological and medical infrastructures in Europe (BIOMEDBRIDGES)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The ESFRI infrastructures in Biological and BioMedical Sciences face substantial challenges in accessing and sharing data and resources. The BioMedBridges consortium brings together the six established ESFRI infrastructures with common goals to define, implement and deliver data interoperability across the biological and biomedical domains.The first objective is to ensure that interoperable stand ...
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 26

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ATMP GMP Open Access Research Alliance - AGORA (AGORA)

Start date: Sep 1, 2013, End date: Oct 31, 2015,

We propose an academic & industrial partnership to facilitate safe and effective delivery of new advanced therapy medicines within the framework of the relevant EU regulations which our previous FP7 funded project have identified as creating unanticipated barriers to development of this field. Over 80% of advanced therapy medicines (ATMPs) trials in the EU are academic investigator led and sponsor ...
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 8

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Biohybrid templates for peripheral nerve regeneration (Biohybrid)

Start date: Oct 1, 2011, End date: Sep 30, 2015,

The BIOHYBRID consortium was build up with the overall aim to develop, in a preclinical perspective, an innovative biohybrid artificial nerve device for the regenerative treatment of traumatic injuries of peripheral nerves. This consortium consists of three active and well integrated SMEs as well as seven academic partners that are recognised leaders in the scientific areas of interest for this pr ...
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 10

 FINISHED 

Understanding chronic pain and improving its treatment (EUROPAIN)

Start date: Oct 1, 2009, End date: Sep 30, 2015,

We will establish an international team of leading researchers and clinicians (EuroPain) to undertake multidisciplinary translational research which will: 1) increase the understanding of chronic pain mechanisms; 2)facilitate the development of novel analgesic drugs; and 3) improve the treatment of chronic pain patients.Nineteen researchers drawn from the London Pain Consortium, the Danish Pain Re ...
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 29

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A Modular Nanosystems Platform for Advanced Cancer Management: Nano-vehicles; Tumor Targeting and Penetration Agents; Molecular Imaging, Degradome based Therapy (SAVEME)

Start date: Mar 1, 2011, End date: Feb 28, 2015,

SaveMe project will address current urgent needs for pancreatic cancer diagnosis and treatment by exploiting partners’ expertise and most recent research achievements for the design and development of novel modular nanosystems platform integrating new functionalized nano-core particles and active agents. The modular platform will enable the design of diverse active nanosystems per diagnostic or th ...
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 23

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Gene Activated Matrices for Bone and Cartilage Regeneration in Arthritis (GAMBA)

Start date: Sep 1, 2010, End date: Aug 31, 2013,

This consortium develops a novel gene-activated matrix platform for bone and cartilage repair with a focus on osteoarthritis-related tissue damage. The S&T objectives of this project are complemented with an innovative program of public outreach, actively linking patients and society to the evolvement of this project. The GAMBA platform is going to implement a concept of spatiotemporal control of ...
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 9

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The impact of Regulation (EC) No 1394/2007 on the development of Advanced Therapy Medicinal Products (ATMPs): an academic perspective (Academic GMP)

Start date: Sep 1, 2010, End date: May 31, 2013,

Advanced Therapy Medicinal Products (ATMPs) are medicinal products for human use, based on gene therapy, somatic cell therapy or tissue engineering. A rapidly growing area in translational research, they represent the ‘next generation’ of complex medicines for complex diseases and pose particular challenges to medicines regulation.Regulation (EC) No 1394/2007 has been designed to ensure the free m ...
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 9

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Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease (EVINCI-study)

Start date: Jan 1, 2009, End date: Jun 30, 2012,

The main purpose of the EVINCI-study is to test the impact of combined “anatomo-functional” non invasive cardiac imaging for detection and characterization of Ischemic Heart Disease (IHD). The EVINCI-study is a prospective clinical European multicenter trial performed in a cohort of 700 patients with suspected IHD. Patients with intermediate pre-test probability will undergo clinical and biohumora ...
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 22