3 European Projects Found
Searched on 125080 European Projects
FINISHED
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)
Start date: Feb 1, 2014, End date: Jan 31, 2019,
We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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30
Partners Participants
FINISHED
The role of NKG2D in CD4+ T cell function and autoimmunity (NKG2D-IMMUNO)
Start date: May 1, 2013, End date: May 29, 2016,
More than 5 million people in Europe live with inflammatory bowel disease (IBD) or rheumatoid arthritis (RA). Both diseases are characterized by chronic inflammation partially mediated by inappropriate T cell response. Effector T-cell responses can be modulated by competing positive or negative costimulatory signals, and dysregulated balance between these signals may lead to chronic autoimmune inf ...
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1
Partner Participant
FINISHED
Long-term PHARMacovigilance for Adverse effects in Childhood arthritis focussing on Immune modulatory drugs (PHARMACHILD)
Start date: Apr 1, 2011, End date: Sep 30, 2014,
Until the age of biotechnology, treatment options for children and adolescents with severe arthritis, inflammatory bowel diseases and other serious diseases with chronic inflammation were limited. Advances in understanding the pathophysiology of the inflammatory responses have led to the development of a new class of medications that are capable of inhibiting selectively the principal mediators of ...
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