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WAKE-UP is an investigator-initiated, multicentre, randomised, double-blind, placebo-controlled trial designed to test efficacy and safety of MRI-based intravenous thrombolysis in patients with wake-up stroke. Every year 1.5 million patients suffer a stroke in the EU. Up to 20% of stroke patients wake up with stroke symptoms. Currently these patients are excluded from thrombolysis which is the onl ...

Computer games represent a vast economic market, a key driver of technology, and an increasingly powerful medium for a broad range of applications. The latest wave of innovation for computer games is 'mobile' and, more precisely, 'location-based'. These outdoors mobile experiences are radically different from traditional computer games or their mobile equivalent. They focus the players' attention ...