Search for European Projects

11 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Advanced Immunization Technologies (ADITEC)

Start date: Oct 1, 2011, End date: Sep 30, 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 FINISHED 

Nuclear Dynamic, Organization and Genome Stability (NDOGS)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The eukaryotic genome is packaged into large-scale chromatin structures occupying distinct domains in the cell nucleus. Nuclear compartmentalization has recently been proposed to play an important role in genome stability but the molecular steps regulated remain to be defined. Focusing on Double strand breaks (DSBs) in response to which cells activate checkpoint and DNA repair pathways, we propose ...
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 1

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Biomarkers For Enhanced Vaccine Safety (BIOVACSAFE)

Start date: Mar 1, 2012, End date: Dec 31, 2016,

BioVacSafe is a concise consortium of selected academic, public, and SME participants used to co-working in industry-led projects, organised into focused Activity Cores to generate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre-development to post-marketing surveil ...
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 24

 FINISHED 

Microbicide Optimization Through Innovative Formulation for Vaginal and Rectal Delivery (MOTIF)

Start date: Oct 1, 2012, End date: Mar 31, 2016,

"The 40% protection against HIV-1 infection with vaginally-applied tenofovir gel demonstrated in the CAPRISA004 trial, has emphasized development of anti-retroviral (ARV)-based microbicides. Combining ARVs in a single product may provide increased protection. Development of a generally applicable formulation platform for combining ARVs (even if chemically incompatible) and understanding of the pro ...
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 9

 FINISHED 

Realizing the European Network in Biodosimetry (RENEB)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently neede ...
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 28

 FINISHED 

Hydroxitirosol, a new generation of microbicides targeting HIV through antiviral and anti-inflammatory pathways (AIM-HIV)

Start date: Dec 1, 2012, End date: May 31, 2015,

Since the first cases of AIDS were reported 30 years ago, HIV remains a difficult target for the research field. Although there is no cure for AIDS, HIV infection can be prevented, however in many countries across the world access to prevention and treatment services is limited. Global leaders have pledged to work towards universal access to HIV prevention and care, so that millions of deaths can ...
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 4

 FINISHED 

European Consortium for Stem Cell Therapy for Neurodegenerative Diseases (NEuroStemCell)

Start date: Dec 1, 2008, End date: May 31, 2013,

The NEuroStemCell consortium will foster collaboration between leading European experimental and clinical researchers in order to maximise the prospects for successful clinical trials of stem cell therapy for Parkinson's (PD) and Huntington's (HD) Disease. The activities will be driven by a Clinical WorkPackage (WP), which will set the requirements, and monitor and guide advances in development of ...
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 15

 FINISHED 

Hybrid Fluorescence Molecular Tomography and X-ray Computed Tomography system and method (FMTXCT)

Start date: Mar 1, 2008, End date: Aug 31, 2012,

"This proposal offers to combine X-ray CT (XCT) and Fluorescence Molecular Tomography (FMT) into a hybrid, quantitative system and method. The project builds on state-of the-art knowledge that only recently became available in different European states as represented by the partners herein. In return it delivers the first such hybrid system worldwide. The system will operate by 1) co-registering ...
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 8

 FINISHED 

Role of astrocytes in Huntington's Disease: characterization of a novel mouse model with targeted expression of mutant huntingtin in the striatum (ASTRO-HD)

Start date: Aug 2, 2010, End date: Aug 1, 2012,

"Huntington’s disease (HD) is an inherited neurodegenerative disease, which has no cure, resulting from the mutation of the gene coding for huntingtin protein (htt). Clinically, HD patients present with progressive involuntary spasmodic movements and cognitive impairments. Post-mortem studies of HD patients reveal severe atrophy of the striatum, reflecting a selective neuronal loss of medium spiny ...
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 1

 FINISHED 

Advanced gene therapy tools for treatment of CNS-specific disorders (NEUGENE)

Start date: Oct 1, 2008, End date: Mar 31, 2012,

"Curative therapies still do not exist for most CNS diseases but gene therapy is a promising new approach. We propose that it will be possible to modify brain function and pathophysiology by targeted delivery of specific curative factors to selected populations of brain cells that are affected by disease. This opens the door for effective treatment regimes, which can be tailored to individual pati ...
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 6

 FINISHED 

The European Advanced Translational Research Infrastructure in Medicine (EATRIS)

Start date: Jan 1, 2008, End date: Dec 31, 2010,

Efficient translation of research discoveries into industrial application is an essential element to maintain Europe’s competitiveness in the biomedical and health industry. The main bottleneck is the lack and the fragmented nature of essential research infrastructure and know-how, leading to unacceptable delays and/or preventing the development of new innovative medicines. The aim of EATRIS is to ...
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