5 European Projects Found
Searched on 125080 European Projects
FINISHED
European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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40
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FINISHED
Comparing the effectiveness of palliative care for elderly people in long term care facilities in Europe (PACE)
Start date: Feb 1, 2014, End date: Jan 31, 2019,
"Aging populations, rising costs and sustainable delivery of high-quality care are increasingly common concerns in all EU countries. PACE aims to perform comparative effectiveness research concerning palliative care in long term care facilities (LTCFs) in Europe. While a growing number of older people will require palliative care in institutionalized settings, palliative care has only recently beg ...
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13
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FINISHED
From Patient Data to Clinical Diagnosis in Neurodegenerative Diseases (PredictND)
Start date: Feb 1, 2014, End date: Jan 31, 2018,
Dementia is a growing health problem with enormous costs to society: the costs currently equal 1% of the global gross-domestic product and a three-fold increase to 115 million dementia cases is expected by 2050. Addressing this grave human and economic challenge requires efficient solutions that do not exist yet: tools to detect and diagnose persons at an early phase, and interventions for delayin ...
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10
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FINISHED
Identifying Inflammatory Bowel Disease causative genes through trans-eQTLs mapping within GWAS loci (TRANS_CEDAR)
Start date: Mar 1, 2014, End date: Feb 29, 2016,
Life-time prevalence of inflammatory bowel disease (IBD) is reaching an alarming rate of > 1/400 in industrialized societies. Improved understanding of disease pathogenesis is essential to develop more effective preventive, diagnostic and therapeutic measures. Genome-wide association studies (GWAS) have identified ~ 160 risk loci contributing to inherited predisposition to Crohn's disease and/or ...
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1
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Identification of regulator variants in Rheumatoid Arthritis and Crohn’s Disease ("""ChIP Seq RA CD""")
Start date: Jun 1, 2012, End date: May 31, 2015,
Rheumatoid Arthritis (RA) and Crohn’s disease (CD) are two common chronic autoimmune and complex diseases where individual susceptibility is determined by a combination of environmental and genetic factors. Almost all of the ~100 risk alleles discovered through recent genetic studies fall in non-coding region and have an elusive function. We hypothesize that risk alleles impact gene regulation by ...
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