Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
Read Project

 21

 FINISHED 

Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union (PERFORM)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar ...
Read Project

 19

 FINISHED 

The artificial pancreas in children aged 1 to 7 years with type 1 diabetes (KidsAP)

Start date: Jan 1, 2017, End date: Jun 30, 2020,

TYPE 1 DIABETES is one of the most COMMON CHRONIC diseases in children with a RAPID increase in number of cases particularly in young children. Type 1 diabetes is associated with LIFE-LONG dependency on insulin administration. POOR glucose control leads to diabetes COMPLICATIONS, e.g. eye, heart, kidney disease, including BRAIN changes in young children. Episodes of VERY LOW glucose levels may be ...
Read Project

 14

 FINISHED 

Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)

Start date: Jan 1, 2015, End date: Dec 31, 2019,

Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
Read Project

 34

 FINISHED 

EUROPLANET 2020 Research Infrastructure (EPN2020-RI)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

The Europlanet 2020 Research Infrastructure (EPN2020-RI) will address key scientific and technological challenges facing modern planetary science by providing open access to state-of-the-art research data, models and facilities across the European Research Area. Its Transnational Access activities will provide access to world-leading laboratory facilities that simulate conditions found on planetar ...
Read Project

 35

 FINISHED 

Screening for Chronic Kidney Disease (CKD) among Older People across Europe (SCOPE) (SCOPE)

Start date: May 1, 2015, End date: Apr 30, 2019,

Chronic kidney disease (CKD) is an important public health problem worldwide, especially in older people. Indeed, population aging in industrialized countries is accompanied by an increase in the prevalence of CKD and its complications. Although its prevalence and the importance of an early diagnosis to prevent complications such as end-renal stage disease (ESRD), screening programme in Europe are ...
Read Project

 11

 FINISHED 

Complex Oscillatory Systems: Modeling and Analysis (COSMOS)

Start date: Jan 1, 2015, End date: Dec 31, 2018,

Many natural and artificial systems are often composed of oscillatory elements which, besides evolving according to their own non-trivial internal dynamics, mutually interact. As a result, many temporal and spatial scales are typically present, often accompanied by the spontaneous emergence of collective properties. Altogether, such features make the task of understanding the resulting evolution a ...
Read Project

 8

 FINISHED 

Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior (MyNewGut)

Start date: Dec 1, 2013, End date: Nov 30, 2018,

Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural diso ...
Read Project

 30

 FINISHED 

RD-CONNECT: An integrated platform connecting registries, biobanks and clinical bioinformatics for rare disease research (RD-CONNECT)

Start date: Nov 1, 2012, End date: Oct 31, 2018,

Despite examples of excellent practice, rare disease (RD) research is still mainly fragmented by data and disease types. Individual efforts have little interoperability and almost no systematic connection between detailed clinical and genetic information, biomaterial availability or research/trial datasets. By developing robust mechanisms and standards for linking and exploiting these data, RD-Con ...
Read Project

 30

 FINISHED 

Contrast by Quadrupole Enhanced Relaxation (CONQUER)

Start date: Sep 1, 2015, End date: Aug 31, 2018,

The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of ...
Read Project

 5

 FINISHED 

Health Care Work Exchange 2016

Start date: Jun 1, 2016, End date: May 31, 2018,

The “Health Care Work Exchange 2016” project will enable 100 apprentices and students of health care vocational schools from 1 June 2016 to 31 May 2018 to carry out an internship in all countries participating in the ERASMUS+ Mobility Program. Apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical techn ...
Read Project

 39

 FINISHED 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Start date: Apr 1, 2016, End date: Mar 31, 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
Read Project

 126

 FINISHED 

Restoration of upper limb function in individuals with high spinal cord injury by multimodal neuroprostheses for interaction in daily activities (MoreGrasp)

Start date: Mar 1, 2015, End date: Feb 28, 2018,

More than half of the persons with spinal cord injuries (SCI) are suffering from impairments of both hands, which results in a tremendous decrease of quality of life (QoL) and represents a major barrier for inclusion in society. Functional restoration is possible with neuroprostheses based on functional electrical stimulation (FES). However, current systems are non-intelligent, non-intuitive open ...
Read Project

 6

 FINISHED 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
Read Project

 19

 FINISHED 

Mars Analogues for Space Exploration (MASE)

Start date: Dec 13, 2013, End date: Jan 1, 2018,

Assessing the habitability of Mars and detecting life, if it was ever there, depends on knowledge of whether the combined environmental stresses experienced on Mars are compatible with life and whether a record of that life could ever be detected. However, our current ability to make these assessments is hampered by a lack of knowledge of how the combined effect of different environmental stresses ...
Read Project

 11

 FINISHED 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Start date: Feb 1, 2012, End date: Oct 31, 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
Read Project

 40

 FINISHED 

European Research Infrastructure on Highly Pathogenic Agents 2 (ERINHA2)

Start date: Jan 1, 2016, End date: Jun 30, 2017,

ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary ...
Read Project

 17

 FINISHED 

Health Care Work Exchange 2015

Start date: Jun 1, 2015, End date: May 31, 2017,

From 1.6.2015 to 31.5.2017 the project “Health Care Work Exchange 2015” will offer 100 apprentices and students of health care vocational schools an opportunity to carry out an internship in all countries participating in ERASMUS+. Foremost apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical technica ...
Read Project

 38

 FINISHED 

The genetic basis of meningococcal and other life threatening bacterial infections of childhood (EUCLIDS)

Start date: Dec 1, 2011, End date: May 31, 2017,

Bacterial infection is the major cause of disability and death in children worldwide. We will use meningococcal disease (MD) as a model to understand genetic factors underlying susceptibility and severity of childhood bacterial infection which will then be applied to other childhood infections. We have established cohorts of patients with MD in Central and Southern Europe (CE,SE), UK and Africa as ...
Read Project

 16

 FINISHED 

Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure (OptimEx)

Start date: Oct 1, 2013, End date: Mar 31, 2017,

More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, affecting 10-20% of the elderly and contributing substantially to hospitalizations of elderly HF patients. Currently, no medic ...
Read Project

 9

 FINISHED 

Clinical Intervention Modelling, Planning and Proof for Ablation Cancer Treatment (ClinicIMPPACT)

Start date: Feb 1, 2014, End date: Jan 31, 2017,

The ClinicIMPPACT proposal builds upon the successful completion of the IMPPACT project (Grant No. 223877, completed in February 2012) that resulted in the creation of a physiological radio-frequency ablation (RFA) model for liver cancer treatment. This preliminary RFA model has been tested in porcine animal studies with extensive histological workup and in a clinical study using patient data for ...
Read Project

 8

 FINISHED 

OncoTrack - Methods for systematic next generation oncology biomarker development (ONCOTRACK)

Start date: Jan 1, 2011, End date: Dec 31, 2016,

We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
Read Project

 22

 FINISHED 

IMmune MOdulating strategies for treatment of MErkel cell Carcinoma (IMMOMEC)

Start date: Jan 1, 2012, End date: Dec 31, 2016,

"Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer of the skin associated with the recently discovered, common Merkel cell polyomavirus (MCV). With an incidence of 0.44 per 100,000 MCC is a very rare cancer. Notably, however, although MCC is 40 times less common than malignant melanoma, MCC has a dramatically higher mortality rate than melanoma rendering MCC to ...
Read Project

 11

 FINISHED 

Cell-based regenerative medicine: new challenges for EU legislation and governance (EUCelLEX)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

This proposal aims at collecting and analysing facts and figures in order to assess the current legislation on the therapeutic use of somatic cells, and to bridge it with the research infrastructure capacity building. Although EU has adopted 3 Directives on Tissues and cells between 2004 and 2006 to harmonise the procurement, storage and use of cells for therapeutic use in Europe, countries have i ...
Read Project

 9

 FINISHED 

European Medicines Research Training Network (EMTRAIN)

Start date: Oct 1, 2009, End date: Sep 30, 2016,

...signed to foster industry/academia mobility and collaboration.The public Consortium is made up of the six pan-European biomedical science (BMS)research infrastructures from the ESFRI roadmap, and the Medizinische Universitaet Wienas managing entity. The six ESFRI-BMS research infrastructures cover a broad spectrum ofcompetences from molecules to humans: structural biology (Instruct), bioinformatic ...
Read Project

 32

 FINISHED 

The Human Brain Project (HBP)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
Read Project

 116

 FINISHED 

A Generic Open-end Simulation Environment for Minimally Invasive Cancer Treatment (Go-Smart)

Start date: Apr 1, 2013, End date: Jun 30, 2016,

The Go-Smart project will build a generic open-source software simulation environment for planning of image guided percutaneous Minimally Invasive Cancer Treatment (MICT). MICT includes radiofrequency ablation (RFA), cryoablation, microwave ablation (MW), transarterial chemoembolisation (TACE), brachytherapy (BT), and prospectively, irreversible electroporation (IRE). Beside of TACE each type of M ...
Read Project

 9

 FINISHED 

Health Care Work Exchange 2014

Start date: Jun 1, 2014, End date: May 31, 2016,

From 1.6.2014 to 31.5.2016 the project “Health Care Work Exchange 2014” will offer 100 apprentices and students of health care vocational schools an opportunity to carry out an internship in all countries participating in ERASMUS+. Foremost apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical technica ...
Read Project

 27

 FINISHED 

Building data bridges between biological and medical infrastructures in Europe (BIOMEDBRIDGES)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The ESFRI infrastructures in Biological and BioMedical Sciences face substantial challenges in accessing and sharing data and resources. The BioMedBridges consortium brings together the six established ESFRI infrastructures with common goals to define, implement and deliver data interoperability across the biological and biomedical domains.The first objective is to ensure that interoperable stand ...
Read Project

 26

 FINISHED 

Vitamin D And LIfestyle Intervention for Gestational Diabetes Mellitus (GDM) Prevention (DALI)

Start date: Mar 1, 2010, End date: Dec 31, 2015,

Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
Read Project

 18

 FINISHED 

The European Network for Translational Research in Atrial Fibrillation (EUTRAF)

Start date: Nov 1, 2010, End date: Oct 31, 2015,

"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
Read Project

 20

 FINISHED 

European Sequencing and Genotyping Infrastructure (ESGI)

Start date: Feb 1, 2011, End date: Jul 31, 2015,

The objective of this project is the integration of world class high-throughput sequencing and genotyping facilities that will provide sequencing and genotyping technologies and data analysis methodologies to the scientific community.The European Sequencing and Genotyping Infrastructure (ESGI) will enable external users to generate data rapidly and to acquire knowledge efficiently. By providing ac ...
Read Project

 11

 FINISHED 

BIOmarkers of Robustness of Metabolic Homeostasis for Nutrigenomics-derived Health CLAIMS Made on Food (BIOCLAIMS)

Start date: Mar 1, 2010, End date: Feb 28, 2015,

The food and health relationship focuses on maintenance of optimal health, both in terms of physiology and new European legislation. Yet, most accepted biomarkers quantify (intermediate) disease endpoints or damage. This has led to major problems in demonstrating health benefits and establishing health claims, and blocks competitive economic and health developments in the food sector. BIOCLAIMS de ...
Read Project

 11

 FINISHED 

ROLE OF ANTISENSE RNAs ON PU.1 REGULATION AND HEMATOPOIESIS (PU.1 Antisense)

Start date: Jan 1, 2012, End date: Dec 31, 2014,

PU.1 levels are critical for normal hematopoiesis and, even modest alterations can lead to leukemia and lymphoma. To achieve optimal expression of the PU.1 gene at different stages of hematopoiesis, multiple interactions are required between its regulatory elements to form fine chromatin architecture. While significant advances have been made in understanding which PU.1 locus chromatin states are ...
Read Project

 2

 FINISHED 

Profiling Responders In Antibody Therapies (PRIAT)

Start date: Nov 1, 2012, End date: Oct 31, 2014,

"Therapeutic antibodies are the largest and fastest growing class of pharmaceutical biotechnology products, with annual sales above 30 billion US$. In some cases, antibody products have revolutionized the management of patients, e.g. TNF-blocking antibodies in Arthritis or Rituxan in lymphoma. However, for most antibody therapies, only a subset of patients benefit from treatment. Thus, there is an ...
Read Project

 8

 FINISHED 

European Research Infrastructure on Highly Pathogenic Agents (ERINHA)

Start date: Nov 1, 2010, End date: Aug 31, 2014,

In the context of the emerging and re-emerging infectious diseases involving highly pathogenic microorganisms, European countries have to be well-prepared to face such threats. However, the Biosafety Level 4 (BSL4) capacity in Europe is not sufficient enough to cover the efficient development of diagnosis, prophylactic and therapeutics means against these pathogens. Moreover, there is no global co ...
Read Project

 27

 FINISHED 

European Research Ethics Committees’ Network (EURECNET)

Start date: Mar 1, 2011, End date: Aug 31, 2014,

EURECNET is a network that brings together national REC associations, networks or comparable initiatives but also other bodies relevant in the field of research involving human participants like National Ethics Councils and the European Commission’s ethical review system. Such a network forms the infrastructural basis to promote awareness of specific working practices of RECs across Europe, to enh ...
Read Project

 22

 FINISHED 

Folate-based nanobiodevices for integrated diagnosis/therapy targeting chronic inflammatory diseases (NANOFOL)

Start date: Dec 1, 2009, End date: Nov 30, 2013,

"NANOFOL proposes to develop a new diagnostic/therapy approach using folate based nanobiodevices (FBN) able to provide a new type of cost efficient treatment for chronic inflammatory diseases such as Atherosclerosis and Rheumatoid Arthritis with low side effects that will constitute a more advantageous solution than current therapies. NANOFOL will achieve all that by fulfilling the following obje ...
Read Project

 14

 FINISHED 

Fatty liver: Inhibition of Progression (FLIP)

Start date: Jan 1, 2010, End date: Jun 30, 2013,

"Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practising hepatogastroenterologist due to the obesity epidemic and its potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. The aim of the FLIP (Fatty Liver: Inhibition of Progression) project is to understand and prevent the progression of liver dis ...
Read Project

 17

 FINISHED 

Standardisation and improvement of generic pre-analytical tools and procedures for in vitro diagnostics (SPIDIA)

Start date: Oct 1, 2008, End date: Mar 31, 2013,

"In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assa ...
Read Project

 17