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"Nuclease Immune Mediated Brain and Lupus-like (NIMBL) conditions, comprising Aicardi-Goutieres Syndrome, Retinal Vasculopathy with Cerebral Leukodystrophy and some cases of Systemic Lupus Erythematosus, are devastating genetic disorders resulting in greatly reduced quality of life, high mortality especially in children, and significant risks of recurrence within affected families. NIMBL condition ...

The Virtual Physiological Human network represents an active and diverse community of biomedical scientists that studies human biology by computational means. This diversity is the basis for an impressive breadth of scientific approaches, and emergent technologies, as well as potentially shareable resources such as data and models. Although in principle, the resources generated are re-usable, in p ...