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A systems biology approach to RESOLVE the molecular pathology of two hallmarks of patients with metabolic syndrome and its co-morbidities; hypertriglyceridemia and low HDL-cholesterol (RESOLVE)
Start date: Jan 1, 2013, End date: Dec 31, 2017,
...oholic fatty liver disease, NAFLD). RESOLVE will deliver on 6 specific objectives:i) build a computational model for analyzing the kinetics of plasma lipids, lipoproteins and their interactions with glucose metabolism.ii) apply the iterative systems biology cycle for calibrating, validating and improving the computational model in dedicated studies in miceiii) build, calibrate and validate the com ...
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