5 European Projects Found
Searched on 125080 European Projects
FINISHED
Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior (MyNewGut)
Start date: Dec 1, 2013, End date: Nov 30, 2018,
Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural diso ...
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30
Partners Participants
FINISHED
European Medical Information Framework (EMIF)
Start date: Jan 1, 2013, End date: Dec 31, 2017,
In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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64
Partners Participants
FINISHED
Determinants of eating behaviour in European children, adolescents and their parents (I.Family)
Start date: Mar 1, 2012, End date: Feb 28, 2017,
Nutrition-related diseases caused a loss of over 56 million years of healthy life of European citizens in 2000. I.Family will make a significant contribution to reduce this burden by studying the interplay and impact of the main drivers of dietary behaviour and food choice. It will take advantage of the unique opportunity to follow-up the large IDEFICS children’s cohort to not only provide added v ...
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17
Partners Participants
FINISHED
Safety Evaluation of Adverse Reactions in Diabetes (SAFEGUARD)
Start date: Oct 1, 2011, End date: Sep 30, 2015,
"In 2010 a widely marketed drug for the treatment of type 2 diabetes (T2DM) (rosiglitazone) was taken from the market as it was associated with an increased risk of myocardial infarction, a T2DM complication it was actually supposed to prevent. This example shows several things. First, the approval requirements do not guarantee a longer term positive benefit risk profile. Second, large scale postm ...
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19
Partners Participants
FINISHED
Arrhythmogenic potential of drugs (ARITMO)
Start date: Jan 1, 2010, End date: Jun 30, 2013,
The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
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