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6 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Regulation of gene expression and cell fate by DNA (hydroxy)methylation (HeavyMethyl)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

(Hydroxy)methylation of cytosine residues in eukaryotic DNA represents a major means to regulate gene expression during development. These modifications are considered to be epigenetic marks, since they have a profound impact on phenotype, but are inherited from mother to daughter cells independent of the underlying DNA sequence. Large efforts are currently underway to profile genome-wide DNA (hyd ...
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 2

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Industry-Academia exchange to further FXR-based therapeutic intervention and non-invasive diagnosis in Inflammatory Bowel Disease (FXR-IBD)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

Inflammatory Bowel Disease (IBD) covers a cluster of disorders characterized by chronic intestinal inflammation which affects approximately 0.2% of the global human population. Current treatment options often fail, are marred by side-effects and undergoing regular endoscopy to monitor and manage the disease is often a burden to the patient.In this study we aim to:1. Develop a novel treatment for I ...
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 3

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European Consortium for High-Throughput Research in Rare Kidney Diseases (EURENOMICS)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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WNT-mediated signal relay in stem cells and oncogenesis - from basic biology to applications (WntsApp)

Start date: Aug 1, 2013, End date: Jul 31, 2017,

The ITN WntsApp is organized to achieve 3 key aims: (i) Provide a committed training programme for young researchers to bridge the gap between basic scientific knowledge and drug development, (ii) Centring research on a key cancer-signalling pathway, WNT signalling, to stimulate synergies and (iii) Strengthening the link between international partners and private enterprises to stimulate innovatio ...
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 10

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TOwards Personalized medicine: defining the role of the bone marrow microenvironment in multiple myeloma (TOP)

Start date: Sep 17, 2012, End date: Sep 16, 2015,

Multiple myeloma (MM), the second most common hematological malignancies, is characterized by an expansion of malignant plasma cells (PCs) in the bone marrow (BM). Despite the development of novel therapies, MM remains an incurable disease with a 5-7 year survival expectancy. MM is usually proceeded by an asymptomatic premalignant state of clonal PC expansion, i.e. MGUS. Progression of MGUS to MM ...
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STEM-TECH: Introducing proprietary stem cell marker technology for the life sciences market (STEM-TECH)

Start date: Feb 1, 2013, End date: Jul 31, 2014,

STEM-TECH has been designed to investigate the commercial opportunity for exploiting our patented stem cell marker technology in the life sciences market. This proprietary technology will meet the need for new enabling technologies that unlock the potential of stem cell detection in academic, industrial and clinical research and practice.THE OPPORTUNITYThe stem cell market is a relatively immature ...
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