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Innate immune recognition of intracellular DNA as 'stranger' and 'danger' signal (IFNDNA)
Start date: Jan 1, 2015, End date: Dec 31, 2018,
"The innate immune system provides an immediate response to infection and injury. It relies on the detection of pathogen-associated molecular patterns (PAMPs), molecular hallmarks of infection which are shared amongst different pathogens but are absent from healthy host cells. The detection of intracellular DNA as PAMP has emerged a key event in the innate immune response to DNA viruses, retrovir ...
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