Search for European Projects

15 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Synergy and antagonism of cholinergic and dopaminergic systems in associative learning (CholAminCo)

Start date: May 1, 2017, End date: Apr 30, 2022,

Neuromodulators such as acetylcholine and dopamine are able to rapidly reprogram neuronal information processing and dynamically change brain states. Degeneration or dysfunction of cholinergic and dopaminergic neurons can lead to neuropsychiatric conditions like schizophrenia and addiction or cognitive diseases such as Alzheimer’s. Neuromodulatory systems control overlapping cognitive processes an ...
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 1

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Restoration of visual perception by artificial stimulation performed by 3D EAO microscopy (VISONby3DSTIM)

Start date: May 1, 2016, End date: Apr 30, 2021,

The long-term aim of the investigation is to assess the feasibility of creating an “artificial sense” and, thereby, a possible sensory (visual) prosthetic. While working towards this goal, we will have to address the question of how neural assembly activity relates to subjective perceptions. Finding and understanding these functional assemblies will make it possible to reactivate them in a precise ...
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 1

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Resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities (THYRAGE)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

We hypothesize that inappropriate thyroid hormone action in target cells is a common mechanism underlying susceptibility to age-related degenerative diseases and co-morbidities. Although regulation of systemic thyroid status is well understood and underpins treatment of common thyroid disease, it is only in the last decade that the importance of local regulation of thyroid hormone action in tissue ...
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 7

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Deciphering the cholinergic modulation of the hippocampal place code. (HippAchoMod)

Start date: Aug 8, 2016, End date: Aug 7, 2019,

... in the proposal I will be acquainted with the cutting edge technologies as well as skills indispensable for starting my independent research group and expanding the research potential of my home institute.
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 1

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Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Start date: Apr 1, 2016, End date: Mar 31, 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

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Modulation of cortical activity by median raphe neuronal assemblies with identified behavioural effects (SERRACO)

Start date: Mar 1, 2012, End date: Feb 28, 2017,

"Cortical operations are built up from states associated with distinct behaviour-dependent network activity patterns that subserve information aquisition, encoding, memory consolidation and retrieval. Thus, they can be considered as manifestations of different processing modes. Groups of modulatory, largely monoaminergic neurons located in subcortical nuclei innervating all forebrain areas are ind ...
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 1

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Quantitative Molecular Map of the Neuronal Surface (MolecMap)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The most fundamental roles of nerve cells are the detection of chemical neurotransmitters to generate synaptic potentials; the summation of these potentials to create their output signals; and the consequent release of their own neurotransmitter molecules. All of these functions require the orchestrated work of hundreds of molecules targeted to specialized regions of the cells. In nerve cells, m ...
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 1

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The Human Brain Project (HBP)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

...imulation, High Performance Computing, Medical Informatics, Neuromorphic Computing and Neurorobotics, and create a user community of research groups from within and outside the HBP, set up a European Institute for Theoretical Neuroscience, complete a set of pilot projects providing a first demonstration of the scientific value of the platforms and the Institute, develop the scientific and technolo ...
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 116

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The role of the basal forebrain in attention and learning (NBATTENTION)

Start date: Jan 1, 2013, End date: Dec 31, 2015,

The basal forebrain (BF) constitutes a major neuromodulatory center, providing extensive projections to the entire forebrain, including all of cortex. Mounting evidence demonstrates that these projections play a key role in cognitive functions, including learning and attention. Damage or deterioration of BF in humans leads to severe cognitive impairments, such as dementia and executive dysfunction ...
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 1

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Switchbox: Maintaining health in old age through homeostasis (SWITCHBOX)

Start date: Feb 1, 2011, End date: Jul 31, 2015,

Healthy aging requires maintenance of homeostatic control of the physiological systems and functions that are integrated by the hypothalamus. Driven by work in previous EU projects (Crescendo/Lifespan) highlighting insulin signalling and the hypothalamic/pituitary/adrenal and thyroid axes in the regulation of aging, SWITCHBOX will examine the flexibility of these neuroendocrine systems in response ...
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 6

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The Integrated Neurobiology of Food Intake, Addiction and Stress (NEUROFAST)

Start date: Apr 1, 2010, End date: Mar 31, 2015,

NeuroFAST is a multidisciplinary project, involving ten teams from seven countries, to explore the neurobiology of addiction and eating behaviour and the complex socio-psychological forces that can lead to its dysregulation. These forces include dietary components (including highly palatable foods and alcohol), some of which may have addictive properties, but also cultural and social pressures, ev ...
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 13

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Nanotechnology: Training Of Experts in Safety (NANOTOES)

Start date: Nov 1, 2010, End date: Feb 28, 2015,

Life Sciences and Nano Sciences interact today mainly in two areas: in the evaluation of accidental health and environmental effects derived from engineered nanomaterials, and in development and biological/clinical evaluation of nanoparticles with intended biological effects for application in medicine and biotechnology. It is essential for producers, distributors, consumers and regulators that th ...
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 12

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Understanding the molecular blueprint and functional complexity of the endocannabinoid metabolome in the brain (BRAINCANNABINOIDS)

Start date: Nov 1, 2009, End date: Oct 31, 2014,

We and others have recently delineated the molecular architecture of a new feedback pathway in brain synapses, which operates as a synaptic circuit breaker. This pathway is supposed to use a group of lipid messengers as retrograde synaptic signals, the so-called endocannabinoids. Although heterogeneous in their chemical structures, these molecules along with the psychoactive compound in cannabis a ...
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 1

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Adenosine receptors in diabetes (HASKODIABETES)

Start date: Apr 1, 2008, End date: Mar 31, 2011,

"Adenosine receptors are expressed on immune cells and other tissues thought to regulate inflammatory events in mammals. Adenosine receptors, when activated by endogenous ligands or exogenous analogs, may repress inflammatory and immune pathways that lead to the destruction of pancreatic islets in models of type I diabetes and islet graft rejection. Building on our observations that inosine and NE ...
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 1

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Training for Intangible assets exploitation

1. Reason for the project: In an increasingly global, knowledge−based economy, the need for a greater understanding of Intellectual Property management is crucial for business success. Many sources, including the World Intellectual Property Organization (WIPO) recognize that the increasing contribution to research and innovation from SMEs is not matched by a widespread awareness of the IP system, ...
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 6