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12 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Novel insights into cardiac regeneration through studies in the zebrafish (zebraHeart)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

Myocardial infarction (MI) leads to cardiomyocyte death and accumulation of myofibroblasts (MFs) at the site of injury, which produce large amounts of extracellular matrix (ECM), generating a scar. Initially, cardiac fibrosis protects from ventricular wall rupture, but subsequent myocardial remodelling causes heart failure, representing a leading cause of death in Europe. While MFs play a central ...
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 2

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CNIC International Postdoctoral Programme (CNIC IPP)

Start date: Jun 3, 2013, End date: Jun 2, 2018,

"The proposed CNIC International Postdoctoral Programme (CNIC IPP) is aimed at supporting trans-national mobility of postdoctoral researchers and to broaden and deepen their individual competence, particularly in terms of acquisition of complementary skills needed to become an independent group leader in the future.The programme offers fellowships for researchers who hold a PhD Degree at the time ...
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 1

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COMBINATIONAL USE OF INNATE IMMUNE RECEPTORS FOR CANCER IMMUNOTHERAPY (PRR IN IMMUNOTHERAPY)

Start date: Jun 1, 2013, End date: May 31, 2017,

Cancer is a major scientific and economical challenge that our society has to face and new therapeutic approaches should now be evaluated in order to decrease human and financial cost of this disease. After suffering from many drawbacks, cancer immunotherapy, which aims at mobilizing the immune system to fight cancer, has recently gained enthusiasm with the completion of several randomized phase I ...
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 1

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Mechanisms of MTOC guidance and Genetic Transfer at the Immune Synapse: novel modes of Immuno-modulation (GENTRIS)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

"Cell-cell synapses are an exquisitely evolved means of communication between cells. During the formation of the immune synapse (IS), diverse transmembrane and membrane associated molecules are reorganized into a highly segregated structure at the T cell–Antigen-Presenting Cell (APC) contact site. As part of this process, the tubulin cytoskeleton is vectorially directed toward the center of the IS ...
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 2

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Clot formation as a potential diagnostic tool and therapeutic target for Alzheimer's disease (ADvasculature)

Start date: Jan 15, 2015, End date: Jan 14, 2017,

Alzheimer’s disease (AD) is the leading cause of dementia in the elderly. Accumulating evidence links AD with vascular risk factors. These correlations, together with profound alterations of cerebrovascular structure and function present in AD, suggest a “vascular hypothesis”, where vascular pathology eventually leads to neurodegeneration and subsequent cognitive decline. A decrease in cerebral bl ...
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 1

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Mitochondrial European Educational Training (MEET)

Start date: Jan 14, 2013, End date: Jan 13, 2017,

"The expanding diversification and specialization of knowledge and the growing complexity of contemporary research in translational research warrant the creation of cooperative multi-disciplinary networks including both basic and medically oriented expertise. This notion is especially true for Mitochondrial Medicine which aims at understanding the physiopathological mechanisms sharing the features ...
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 10

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Homeostatic regulation of mesenchymal stem cells in the haematopoietic stem-cell niche (MSC-HSC NICHE)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The cells forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear. Our recent studies have demonstrated that mesenchymal stem cells (MSC) identified using expression of the intermediate filament protein nestin constitute an essential HSC niche component. Nestin+ cells contribute to bone formation, contain all the mesenchymal activity and can self-renew and expand in serial ...
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 1

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Living Photonics: Monitoring light propagation through cells (LiPhos)

Start date: Nov 1, 2012, End date: Oct 31, 2015,

LIPHOS is focused on the development of completely innovative biophotonic diagnosis tools, which are for the first time implemented using cells as constituent material. Here, and unlike existing systems, light remains confined in a waveguide whose core is uniquely composed by cells, giving rise to the "Living photonics" concept. In this context, cells play a two-fold role: i) they form the biomate ...
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 8

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CNIC INTERNATIONAL INCOMING FELLOWSHIPS FOR YOUNG GROUP LEADERS (CNIC IIF)

Start date: Oct 1, 2011, End date: Sep 30, 2015,

The CNIC IIF Programme will offer a total of 24 positions during the COFUND programme life (four years) in the incoming mobility type in the area of cardiovascular research.Every year six fellowships will be offered at the level of young group leaders: 4 Starting Fellowships (SF) and 2 Advanced Fellowships (AF). In both cases, the duration of the fellowships will be 3 years and have particular ob ...
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 1

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Oxygen sensing in cardiovascular progenitors cell fate decisions (Hypoxia & Cell Fate)

Start date: Mar 1, 2011, End date: Feb 28, 2015,

Cardiogenesis is a complex process that involves different cell types that have to mature to form the final functional heart compartments. Isl1 cardiovascular progenitors label the “second heart field” and contribute to myocardial, smooth muscle and endothelial structures of the heart. These progenitors have been extensively studied but little is know about the extracellular signals mediating thei ...
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 1

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Molecular mechanisms of mature B cell lymphomagenesis (BCLYM)

Start date: Dec 1, 2008, End date: Nov 30, 2014,

Most of the lymphomas diagnosed in the western world are originated from mature B cells. The hallmark of these malignancies is the presence of recurrent chromosome translocations that usually involve the immunoglobulin loci and a proto-oncogene. As a result of the translocation event the proto-oncogene becomes deregulated under the influence of immunoglobulin cis sequences thus playing an importan ...
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 2

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Role of PPARgamma in the interstitial fluid volume regulation and contribution to cardiovascular complications of TZDs (PGFC)

Start date: Oct 1, 2009, End date: Sep 30, 2011,

"Thiazolidinediones (TZDs) are clinically proven insulin sensitizers with anti-inflammatory benefits used in the therapy of type 2 diabetes mellitus (T2DM) and atherosclerosis. TZDs can activate a transcription factor, the peroxisome proliferator-activated receptor gamma (PPARg). PPARg regulates expression of several genes involved in inflammatory pathways, lipid transport and carbohydrate metabol ...
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 1