Search for European Projects

3 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics (3D NEONET)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascul ...
Read Project

 18

 FINISHED 

Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer (CAM-PAC)

Start date: Nov 1, 2013, End date: Oct 31, 2018,

Cancers are genetic disease arising from the accumulation of multiple molecular alterations in affected cells. Large-scale genomic, transcriptomic and proteomic analyses have established comprehensive catalogues of molecules which are altered in their structure and/or abundance in malignant tumors as compared to healthy tissues. Far less developed are concepts and methods to integrate data from di ...
Read Project

 18

 FINISHED 

Predicting individual response and resistance to VEGFR/mTOR pathway therapeutic intervention using biomarkers discovered through tumour functional genomics (PREDICT)

Start date: Jan 1, 2011, End date: Dec 31, 2014,

...h through personalised tumour cDNA derived-shRNA library transduction of ex-vivo cultured autologous tumour cell lines. Bioinformatics integration of these complementary individualised clinical and experimental datasets will enable the rapid and cost efficient identification of predictive biomarkers and simultaneously define molecular mechanisms contributing to intrinsic and acquired drug resistan ...
Read Project

 16