Search for European Projects

7 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Regulation of inflammasome activity through NLRP3 ubiquitination level (UbInflam)

Start date: Jan 1, 2015, End date: Dec 31, 2019,

The innate immunity constitutes an efficient barrier by rapidly detecting pathogens and tissue damages through pattern recognition receptors including NLRP3. On the other hand, inappropriate NLRP3 activation causes deleterious inflammation and contributes to various conditions including atherosclerosis, diabetes, gout and Alzheimer's diseases. Therefore NLRP3 requires tight regulation that remains ...
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 1

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The Human Early-Life Exposome – novel tools for integrating early-life environmental exposures and child health across Europe (HELIX)

Start date: Jan 1, 2013, End date: Jun 30, 2017,

The aim of HELIX is to exploit novel tools and methods (remote sensing/GIS-based spatial methods, omics-based approaches, biomarkers of exposure, exposure devices and models, statistical tools for combined exposures, novel study designs, and burden of disease methodologies), to characterise early-life exposure to a wide range of environmental hazards, and integrate and link these with data on majo ...
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 16

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What You Say Is What You Did (WYSIWYD)

Start date: Jan 1, 2014, End date: Dec 31, 2016,

The What You Say Is What You Did project (WYSIWYD) will create a new transparency in human robot interaction (HRI) by allowing robots to both understand their own actions and those of humans, and to interpret and communicate these in human compatible intentional terms expressed as a language-like communication channel we call WYSIWYD Robotese (WR). WYSIWYD will advance this critical communication ...
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 7

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AUTOPHAGY AND VIRULENCE OF HEPATITIS C VIRUS (HepATG)

Start date: Aug 1, 2012, End date: Jul 31, 2016,

Autophagy is a major intracellular pathway for cellular homeostasis. It also plays an essential role in antiviral response against diverse pathogens. Indeed, in addition to the removal of viral protein aggregates from the cells, autophagy is emerging as a key regulator of viral propagation by regulating positively or negatively the secretion of interferon α/β (IFNα/β) and inflammatory molecules, k ...
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 1

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Reproductive Biology Early Research Training (REPRO-TRAIN)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The “Reproductive Biology Early Research Training” network (REPRO-TRAIN) aims to provide all the elements required to train the nextgeneration of researchers with the latest skills to solve the current societal problems in male reproductive biology (Andrology). Thedecline in sperm counts and concomitant increase in testicular cancer demands research in this field as an urgent priority.Spermatogene ...
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 8

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New Algorithms for Host Pathogen Systems Biology (SYSPATHO)

Start date: Oct 1, 2010, End date: Mar 31, 2015,

SYSPATHO focuses on the development of novel and generally applicable mathematical methods and algorithms for systems biology. These methods and algorithms will be applied to study the complex interactions of hepatitis C virus (HCV), a human-pathogenic virus of high medical relevance, with its host at the systems level. Using a multidisciplinary, integrative approach, PATHOSYS will (a) develop met ...
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 11

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Role of microRNAs in host responses to Crohn's disease-associated adherent-invasive Escherichia coli (MiRNA-AIEC)

Start date: Aug 1, 2012, End date: Jul 31, 2014,

Recent studies have shown dysregulation of microRNAs (miRNAs) in the mucosa of Crohn’s disease (CD) patients, suggesting a role for miRNAs as contributors to inflammatory bowel disease (IBD) susceptibility. The scientists from the host institution previously showed that ileal lesions in CD patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC), which are able to invade and ...
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