6 European Projects Found
Searched on 125080 European Projects
FINISHED
PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform (PRETREAT)
Start date: Jan 1, 2016, End date: Dec 31, 2019,
Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, togeth ...
Read Project
6
Partners Participants
FINISHED
"Multimodular biomarker analysis workflow for diagnosis, prognosis and monitoring of drug treatment response in bladder cancer" (DIPROMON)
Start date: Nov 1, 2012, End date: Oct 31, 2016,
"With the advent of Omics technologies capable of profiling substantial fractions of molecular entities from the genome down to the metabolome level a significant boost in understanding disease pathophysiology, consequently providing tailored diagnostics and therapy, was expected. With impressive results for selected diseases, cancer still sees significant shortcomings. One reason for this clinica ...
Read Project
6
Partners Participants
FINISHED
Markers for Sub-Clinical Cardiovascular Risk Assessemnt (EU-MASCARA)
Start date: Dec 1, 2011, End date: May 31, 2016,
EU-MASCARA is a collaborative project that aims to improve diagnosis of cardiovascular diseases and prediction of cardiovascular risk by analysing a panel of biomarkers. EU-MASCARA aims to examine genetic, proteomic and metabolomic markers together with markers of inflammation, oxidative stress and cardiac remodelling to study their incremental diagnostic and predictive value over and above existi ...
Read Project
16
Partners Participants
FINISHED
Ovarian Cancer Therapy – Innovative Models Prolong Survival (OCTIPS)
Start date: Jan 1, 2012, End date: Dec 31, 2015,
"About 75% of advanced epithelial ovarian cancer (EOC) patients respond to first-line surgery and chemotherapy but most relapse and ultimately acquire platinum resistance which soon leads to death. Relapsed high grade serous ovarian cancer (HGSOC) is the single main cause of EOC-related morbidity and mortality (despite the fact that HGSOC is highly chemosensitive). We hypothesize that the primary ...
Read Project
11
Partners Participants
FINISHED
Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)
Start date: Jan 1, 2010, End date: Dec 31, 2014,
Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
Read Project
30
Partners Participants
FINISHED
Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics (Predict-IV)
Start date: May 1, 2008, End date: Oct 31, 2013,
The overall aim of Predict-IV is to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico modelling, in a rapid and cost effective manner. A better prediction of the safety of an investigational compound in early develo ...
Read Project
