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Epilepsy is a devastating condition affecting over 50 million people worldwide. This multidisciplinary project is focused on the process leading to epilepsy, epileptogenesis, in adults. Our main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and development of seizures. Our central premise and vision is that a comb ...

"A significant part of the costs of neurological diseases on society is associated with epilepsy. About 30-40% of the patients are refractory to pharmacological treatments, which are mostly symptomatic and often have side effects. In few cases surgical intervention is considered and no treatments interfering with or preventing the development of epilepsy are currently available. In this context, E ...