18 European Projects Found
Searched on 125080 European Projects
FINISHED
REgenerative Stem cell therapy for STroke in Europe (RESSTORE)
Start date: Sep 1, 2015, End date: Aug 31, 2020,
...g preclinical and pilot clinical evidences, RESSTORE will focus on the clinical assessment of regenerative cell therapy to improve stroke recovery and patients quality of life. RESSTORE European multicentre randomised phase IIb will explore, for the first time, the efficacy (functional recovery) and safety of intravenous infusion of allogenic adipose tissue derived mesenchymal stem cells (ADMSCs) ...
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29
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European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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40
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Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies (SPRINTT)
Start date: Jul 1, 2014, End date: Jun 30, 2019,
The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from the expansion of an older population with specific medical needs related to multiple chronic disorders. As a consequence, the medical conditions of a large and growing seg ...
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27
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Lifecourse biological pathways underlying social differences in healthy ageing (LIFEPATH)
Start date: May 1, 2015, End date: Apr 30, 2019,
"The dramatic differentials in healthy ageing, quality of life and life expectancy between individuals of different socioeconomic groups, is a major societal challenge facing Europe. The overarching aim of the LIFEPATH project is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This will be achieved via an original study de ...
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18
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Clinical trial of autologous adipose-derived mesenchymal stromal cells (ASC) in the treatment of mild to moderate osteoarthritis (ADIPOA2)
Start date: Jan 1, 2015, End date: Dec 31, 2018,
...(ASCs) are attractive for cellular therapy given the abundance of tissue, high frequency of MSCs and minimally invasive harvest procedure. The EU consortium ADIPOA has shown in a ‘first in man’ 2-centre Phase I safety study that intraarticular injection of a single dose of autologous ASCs to the knee (18 patients, 12 month follow-up) was well-tolerated, had no adverse effects, and resulted in an i ...
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20
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Towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe (EUthyroid)
Start date: Jun 1, 2015, End date: May 31, 2018,
Despite the fact that iodine deficiency (ID) can easily be prevented by iodine fortification of table salt, industrial salt and cattle food, Europe belongs to the worst regions in terms of access to iodized salt and is seriously ID, resulting in the perpetuation of the single most important, preventable cause of brain damage. European ID is due to significant heterogeneity in prevention and monito ...
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33
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Utility of omic-based biomarkers in characterizing older individuals at risk for frailty, its progression to disability and general consequences to health and well-being - The FRAILOMIC Initiative (FRAILOMIC)
Start date: Jan 1, 2013, End date: Dec 31, 2017,
The forecasted increase in the number of older people for this century will be accompanied by an increase of those with disabilities. Disability is usually preceded by a condition named frailty that encompasses changes associated with ageing, life styles and chronic diseases. To detect and intervene on it is of outstanding importance to prevent disability, as recovery from disability is unlikely. ...
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29
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Reach α-synuclein-dependent neurodegeneration: clinical development of therapeutic AFFITOPE vaccines for Parkinson’s disease and multisystem atrophy (SYMPATH)
Start date: Oct 1, 2013, End date: Sep 30, 2017,
...trategy, uses the synergy resulting from applying 2 vaccine candidates in 2 complementary indications linked through their pathology. TANDEM PD/MSA capitalizes on (i) excellent clinical research centres and their associated national/European networks, (ii) platform methods assessing aSyn species as candidate biomarkers and (iii) preliminary clinical experience with PD01A, the first aSyn targeting ...
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8
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VitaminD3-Omega3-Home Exercise- HeALTHy Ageing and Longevity Trial (DO-HEALTH)
Start date: Jan 1, 2012, End date: Jun 30, 2017,
...a-3 fatty acids and physical exercise. However, their individual and combined effects have yet to be confirmed in a clinical trial. The DO-HEALTH will close this knowledge gap in a large 3-year multi-centre clinical trial that will establish long-term efficacy and safety data for the 3 interventions in the prevention of age-related diseases in seniors.The DO-HEALTH trial will enrol 2152 community- ...
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25
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A RANDOMIZED CLINICAL TRIAL TO EVALUATE THE EFFECTIVENESS OF A MULTI-MODAL INTERVENTION IN OLDER PEOPLE WITH TYPE 2 DIABETES ON FRAILTY AND QUALITY OF LIFE: THE MID-FRAIL STUDY (MID-FRAIL-STUDY)
Start date: Mar 1, 2012, End date: Apr 30, 2017,
The prevalence of diabetes in people ≥ 65 years approaches 25% (40% of all patients with diabetes are > 65 years). This number will increase 4-fold in people > 70 years in 2050. Diabetes results in a high personal and social health burden, and a significant public health burden in terms of rising healthcare costs. Diabetes is associated with increased functional decline in older people and may exp ...
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17
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Clinical European study on the outcome of surgical and hormonal therapy and psychological intervention in disorders of sex development (DSD) (DSD-LIFE)
Start date: Oct 1, 2012, End date: Mar 31, 2017,
Disorders of sex development (DSD) are a conglomerate of rare diseases with an estimated incidence of 1: 4500. The causes of DSD are mainly disorders with gonadal dysgenesis, decreased androgen synthesis or function in XY males or disorders with elevated androgen production in XX females. Decision on sex of rearing is difficult in some cases as the prenatal androgen imbalances result in ambiguous ...
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17
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PROMOTE PHYSICAL EXERCISE IN FRAIL ELDERLY
Start date: Jan 1, 2015, End date: Dec 31, 2016,
VIVIfy is born to support European health systems handle the challenges of efficient care provision and system reorganisation, and meet future needs, related to an ageing and frailty society, through the search for formulas that improve quality of life, putting in value the positive effects of sport and exercise programmes. Establishing synergies among sport, health, social care, and education sys ...
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7
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Best EScalation Treatment in Multiple Sclerosis (MS) (BEST MS)
Start date: Nov 1, 2012, End date: Oct 31, 2016,
"Multiple Sclerosis (MS) is a devastating disease of the central nervous system affecting 2.5 million worldwide. MS is a field of constant therapeutic innovation, a fact which brings hope to young adults since MS is one of the most frequent causes of severe handicap. A major unmet need is to rationalize treatment decisions. To date, there is no way of predicting which patients will best respond to ...
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5
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Red Transfronteriza de Investigación Biomédica de los Pirineos- Establecimiento de una Red de colaboración estable entre Centros de Investigación Biomédica en el espacio Pirineos (BIOMED-PIRINEOS)
Start date: May 31, 2012, End date: Nov 29, 2014,
... Pyrénées Limousin,Instituto Aragonés de Ciencias de la Salud (IACS), Université Paul Sabatier de Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU), Fundación Vasca de Innovación e Investigación Sanitarias (BIOEF), Centro de Investigación Biomédica de La Rioja (CIBIR) e Instituto de Investigación Biosanitaria (BIODONOSTIA).
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8
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Improving health services for European citizens with dementia: Development of best practice strategies for the transition from ambulatory to institutional long-term care facilities (RightTimePlaceCare)
Start date: Jan 1, 2010, End date: Sep 30, 2013,
Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best practice strategies for long-term care. RightTimePlace ...
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8
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Diagnostic Enhancement of Confidence by an International Distributed Environment (DECIDE)
Start date: Sep 1, 2010, End date: Feb 28, 2013,
DECIDE (Diagnostic Enhancement of Confidence by an International Distributed Environment), aims at creating a e-Infrastructure to enhance the diagnostic confidence in chronic brain diseases such as Alzheimer and dementia. Proper management of these neurodegenerative diseases are thought to be very important in terms of health-economical point of view. The DECIDE infrastructure will provide the med ...
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13
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The e-MEDICINimage project enabled the creation of a remote continuing education scheme in the health sector (medical biology) related to parasitology and medical mycology. These two training schemes are built exclusively on e-Learning techniques and each of them offers a unique curriculum available in 5 languages (English, Spanish, French, Polish and Portuguese). This scheme, associated with the ...
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16
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Le projet a pour but de rapprocher la Communauté médicale de la Clinique Universitaire de Navarre, de celle de lHopital Rangueil du CHU de Toulouse. Il sinscrit dans le cadre des liens forts de coopération déja tissés entre les deux partenaires parmi lesquels peut etre cité le projet de recherche sur la Thérapie Cellulaire qui a été accepté en 2002. Il permettra un meilleur suivi sur cette recherc ...
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