5 European Projects Found
Searched on 125080 European Projects
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Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen (U-PGx)
Start date: Jan 1, 2016, End date: Dec 31, 2020,
Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and ...
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16
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Point-of-care microfluidic device for quantification of chemotherapeutic drugs in small body fluid samples by highly selective nanoparticle extraction and liquid crystal detection (DiaChemo)
Start date: May 1, 2015, End date: Apr 30, 2019,
The decision-making in chemotherapy nowadays depends on standard methods that are liquid chromatography (LC-MS/MS) followed by mass spectrometry or capillary electrophoresis; both are labour- and cost-intensive and can be performed only in dedicated hospitals and laboratories. This lead to a minimal therapeutic drug monitoring in patients and hence that 30-60% of drugs are administered without cli ...
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9
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"Molecular Nanotechnology for Life Science Applications: QUantitative Interactomics for Diagnostics, PROteomics and QUantitative Oncology" (QUIDPROQUO)
Start date: Jul 1, 2011, End date: Jun 30, 2016,
"The main goal of this proposal is to introduce innovative devices and protocols (based on nano- manipulation, the response of micro-(nano-)mechanical oscillators and nano-fluidics) to carry out, precise, high throughput, high sensitivity, and low cost interactomic measurements. We aim at measuring, in parallel, the concentration of up to several proteins or non-coding RNA molecules, in samples do ...
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2
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Transposon based Forward Genetic Screen for the Identification of ncRNAs involved in Colorectal Cancer Metastasis (Transposon get ncRNA)
Start date: Mar 1, 2012, End date: Aug 11, 2015,
In the era of target-based cancer therapies there is still missing a univocal hit for treating cancer metastatic spread, which is ultimately the main cause of cancer death. Non-protein-coding RNA transcripts (ncRNAs) were for long regarded as transcriptional noise; interestingly, it turns out that most of the genome does not carry protein-coding genes (PCGs) and yet is transcribed in a development ...
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1
Partner Participant
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Slovenian-Italian genetics network (SIGN)
Start date: Oct 31, 2011, End date: Oct 30, 2014,
Coordination between public health institutions and their cooperation with universities, as well as access to key experts in cross-border region Expected Results: The establishment of cross-border functional center in the fiel ...
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