Search for European Projects

19 European Projects Found

Searched on 125080 European Projects

 FINISHED 

"Health and the Understanding of Metabolism, Aging and Nutrition" (HUMAN)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

"Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in most cases, yet to be elucidated. The evolutionary distance of most animal models from humans represents a major limitation fo ...
Read Project

 17

 FINISHED 

European Initial Training Network on Developmental and Computational Biology (DevCom)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The ability to manipulate cellular pluripotency and differentiation holds the as yet unrealized promise of regenerative medicine to produce replacement cells and tissues. To this end a deep understanding of the regulation of differentiation potential in the context of normal embryonic development is crucial. The recent revolution in sequencing technology has enabled high throughput and genome-wide ...
Read Project

 8

 FINISHED 

Persia and its Neighbours: the Archaeology of Late Antique Imperial Power in Iran (PERSIA)

Start date: May 1, 2012, End date: Apr 30, 2017,

The Sasanian Empire (3rd-7th c. AD) stretched from Mesopotamia to the west of the Indian Subcontinent. A pilot study has shown that major frontier walls and geometrical fortifications, whose scale and sophistication surpasses those in contemporary Europe, date to the Sasanian era, as do grand urban foundations and canal systems. Yet, excavations and surveys of Sasanian monuments have been far and ...
Read Project

 7

 FINISHED 

Love wave fully integrated Lab-on-Chip platform for food pathogen detection (LOVE-FOOD)

Start date: Sep 1, 2012, End date: Feb 29, 2016,

The project is aimed at developing a fully integrated lab-on-chip microsystem platform, performing multimodal analysis of several analytes combining nucleic acid and whole bacteria detection. The system will allow directly and without prior culture the identification in one single run of a multiplicity of pathogens and their specific sequences responsible will be targeted and identified. The heart ...
Read Project

 8

 FINISHED 

Integrated research on DEvelopmental determinants of Aging and Longevity (IDEAL)

Start date: Feb 1, 2011, End date: Jan 31, 2016,

"IDEAL will obtain insight into the role of early life conditions affecting late-life health, disease and aging, and the role of epigenetic regulation therein. IDEAL will identify the determinants and targets of this epigenetic regulation utilizing a resource of unique human cohorts and animal studies that allow testing of hypotheses on the link between development and aging.Key objectives of IDEA ...
Read Project

 16

 FINISHED 

Drastically reduced use of rare earths in applications of magnetocalorics (DRREAM)

Start date: Jan 1, 2013, End date: Dec 31, 2015,

"We will examine the life cycle of rare earth metals used in magnetic phase change technologies. Our primary focus is on room temperature magnetic cooling, a near-market solid state alternative to gas compression in which a phase change “magnetocaloric” material is magnetised by a permanent magnet. We will address the fabrication, manufacture and use of the magnetocaloric material, aiming: (1) ...
Read Project

 8

 FINISHED 

Temporal Reasoning with Data for Verification (DataVerif)

Start date: Aug 1, 2012, End date: Jul 31, 2015,

The development of formal methods for the verification of computer systems is recognizedas a grand challenge by many research institutions. A successful approach for the verification ofsystems consists in modelling the system to be verified by a mathematical structure andin expressing behavioral properties in a logical formalism. The assumption that programs arefinite-state is usually too restrict ...
Read Project

 1

 FINISHED 

Switchbox: Maintaining health in old age through homeostasis (SWITCHBOX)

Start date: Feb 1, 2011, End date: Jul 31, 2015,

Healthy aging requires maintenance of homeostatic control of the physiological systems and functions that are integrated by the hypothalamus. Driven by work in previous EU projects (Crescendo/Lifespan) highlighting insulin signalling and the hypothalamic/pituitary/adrenal and thyroid axes in the regulation of aging, SWITCHBOX will examine the flexibility of these neuroendocrine systems in response ...
Read Project

 6

 FINISHED 

A systems biology approach to dissect cilia function and its disruption in human genetic disease (SYSCILIA)

Start date: Jun 1, 2010, End date: May 31, 2015,

AIM: To identify the molecular mechanisms characterizing cilium function, and the discrete perturbations associated with dysfunction caused by mutations in inherited ciliopathies, applying a systems biology approach. BACKGROUND: Cilia are microtubule-based, centriole-derived projections from the cell surface. They transduce extracellular signals and regulate key processes in which signals of the e ...
Read Project

 17

 FINISHED 

Epigenetic and genome stability: non coding RNA-mediated chromatin modifications in S. cerevisiae (EPIncRNA)

Start date: Dec 1, 2009, End date: Nov 30, 2014,

Our project is to understand the role of non coding (nc)RNA in the regulation of epigenetic landscape and gene expression. RNA interference pathway is absent in the budding yeast but recent works from our laboratory showed the existence of an original ncRNA-dependent pathway that controls gene expression in S. cerevisiae. We characterized a cryptic unstable ncRNA mediating the transcriptional sile ...
Read Project

 1

 FINISHED 

Reproduction of European Eel: Towards a Self-sustained Aquaculture (PRO-EEL)

Start date: Apr 1, 2010, End date: Jul 31, 2014,

The recent decline of European eel (Anguilla anguilla) and no signs of recovery has brought attention to the biologically unsustainable exploitation of the stock. In September 2007, the EU has adopted the Council Regulation 1100/2007 establishing measures for the recovery of the European eel stock. However, eel are still fished intensively for human consumption while aquaculture and restocking rel ...
Read Project

 15

 FINISHED 

(International) Socio-Technical Challenges for implementing geological disposal (INSOTEC)

Start date: Mar 1, 2011, End date: Jun 30, 2014,

InSOTEC aims at identifying the main socio-political challenges for implementing geological disposal and their interplay with technical challenges. It will furthermore provide the IGD-TP with concrete suggestions on how to address these entangled socio-technical challenges.The biggest challenge today lies in adapting the generic concept of geological disposal to the real world environment (both na ...
Read Project

 17

 FINISHED 

Balancing selection and the molecular evolution of mimicry supergenes (MimEvol)

Start date: Feb 1, 2010, End date: Jan 31, 2014,

How genome organisation and architecture respond to variations in selection regimes is indeed poorly known at the microevolutionary scale. Supergenes are tight clusters of genes which simultaneously control the variation of various components of a complex trait, involving elements with different ontology1-4. Supergenes typically evolve in response to strong epistatic selection between neighbouring ...
Read Project

 1

 FINISHED 

Neuroendocrine Immune Networks in Ageing (NINA)

Start date: Dec 1, 2009, End date: Nov 30, 2013,

Current demographic trends indicate that by the year 2020 almost 1 in 5 of the European population will be aged over 65. However, although life expectancy is increasing in the developed world, the period of good health enjoyed by its people is not keeping pace. The ageing population is thus a major health and economic issue for Europe. Although ageing is a complex process, we know much about its a ...
Read Project

 9

 FINISHED 

Lactase persistence and the Cultural History of Europe (LeCHE)

Start date: Sep 1, 2008, End date: Aug 31, 2012,

The ideal training for future researchers in Europe, draws together leading groups in the world, state-of-the-art methods and a clearly focused, important and emotive questions with widespread repercussions, and integrates them using sophisticated tools and training devices; welcome to LeCHE. This large (14 researcher, 24 participant) training network explores the origin and impact of dairying Eur ...
Read Project

 13

 FINISHED 

SME-Academia Nuclear Receptor Knowledge Transfer (SME RECEPTOR)

Start date: Jun 1, 2008, End date: May 31, 2012,

"SME RECEPTOR is a transfer of knowledge programme which will bring top scientists from industry and academia together to address key questions in nuclear receptor research. The programme of research, which is implemented through the two way exchange of researchers between three leading research organisations and three specialist innovative SMEs, will develop methodology to tackle one of the most ...
Read Project

 6

 FINISHED 

Solid State Energy Efficient Cooling (SSEEC)

Start date: Oct 1, 2008, End date: Sep 30, 2011,

We propose to develop a high efficiency heat pump and an air conditioner based on a magnetic refrigeration cycle. Both devices will operate at room temperature. The core materials research will centre around the identification, synthesis, modeling and production of low cost, environmentally friendly magnetic refrigerant materials that operate in low magnetic fields and the synthesis and production ...
Read Project

 8

 FINISHED 

Fictions and arguments of Plato’s dialogues (PLATO’S FICTIONS)

Start date: Sep 21, 2009, End date: Sep 20, 2011,

"The project examines the modalities, place, status, and roles of fictional elements in Platonic dialogues. The Applicant proposes an inquiry into the nature of Platonic fiction based on a selection of characteristic themes offered as fictional by characters in various Plato’s dialogues. The analysis will aim at a better understanding of the modes of fictionality Plato used, and, as a result, of t ...
Read Project

 1

 FINISHED 

Corrosion protection with perfect atomic layers (CORRAL)

Start date: Sep 1, 2008, End date: Aug 31, 2011,

The aim of this project is to develop high density defect-free ultra-thin sealing coatings with excellent barrier properties and improved corrosion resistance. Their successful functioning will be provided by the synergy of the coating “perfect” morphology and its complex structural design, which can be tailored at the nanoscale. The study will be focused on development of novel nanostructured coa ...
Read Project

 15