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Neurotransmitter Cys-loop receptors: structure, function and disease (NeuroCypres)
Start date: Feb 1, 2008, End date: Jul 31, 2012,
Cys-loop receptors (CLRs) form a superfamily of structurally related neurotransmitter-gated ion channels, comprising nicotinic acetylcholine, glycine, GABA-A/C and serotonin (5HT3) receptors, crucial to function of the peripheral and central nervous system. CLRs cover a wide spectrum of functions, ranging from muscle contraction to cognitive functions. CLR (mal)function is linked to various disord ...
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