Search for European Projects

14 European Projects Found

Searched on 125080 European Projects

 FINISHED 

New experimental therapeutic approaches for Parkinson’s disease by direct DA neuronal reprogramming (REPROPARK)

Start date: Jun 1, 2014, End date: May 31, 2019,

Neurodegenerative diseases cause a significant burden on the elderly population in Europe. Parkinson’s disease (PD) affects 1.2 million people in Europe and with the increasing life expectancy this number will rise, putting more pressure on health care. Treatment of PD is only symptomatic, and therefore, there is an urgent need for more efficient therapies. Degeneration of mesencephalic DA neurons ...
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 2

 FINISHED 

Ensuring the Integrity of the European food chain (FOODINTEGRITY)

Start date: Jan 1, 2014, End date: Dec 31, 2018,

Food Integrity “the state of being whole, entire, or undiminished or in perfect condition”.Providing assurance to consumers and other stakeholders about the safety, authenticity and quality of European food (integrity) is of prime importance in adding value to the European Agri-food economy. The integrity of European foods is under constant threat from fraudulently labelled imitations that try to ...
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 64

 FINISHED 

LEGumes for the Agriculture of TOmorrow (LEGATO)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

The project has been conceived to promote the culture of grain legumes in Europe by identifying priority issues currently limiting grain legume cultivation and devising solutions in term of novel varietal development, culture practices, and food uses. LEGATO will develop tools and resources to enable state of the art breeding methodology and to exploit fully the breadth of genetic resources avail ...
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 32

 FINISHED 

Immunostimulatory Agonist antibodies for Cancer Therapy (IACT)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

...cer type and treatment regimen have been selected to approximate pre-clinical settings in which striking therapeutic impact with agonist IS-Abs has been obtained. These studies will involve extensive analysis of efficacy-related biomarkers by means of validated assays, not only in blood samples, but also in the most relevant compartment: the tumor microenvironment. While our state-of-the-art agoni ...
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 11

 FINISHED 

The role of miRNAs in KRAS-driven Non-Small Cell Lung Cancer (KRASmiR)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

Lung cancer is the leading cause of death by cancer in Europe. Non-small cell lung cancer (NSCLC) represents about 80% of total lung cancers. KRAS is the most commonly mutated oncogene in NSCLC, found in over 20% of patients. Since KRAS mutations are directly responsible for NSCLC, KRAS represents a relevant target to prevent NSCLC development. Yet, efforts to develop therapeutic inhibitors have f ...
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 1

 FINISHED 

The European non-coding RNA network (RNATRAIN)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

"Non-coding RNA (ncRNA) is a new research field in rapid development. It holds the potential to explain many fundamental biological phenomena and there is a vast prospective for the development of ncRNA-derived diagnostic and therapeutic tools. Hence, biotech and pharmaceutical companies are actively looking into this unexplored territory for novel targets. Therefore, there is a substantial and un ...
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 11

 FINISHED 

Supply-rate depression as endogenous anti-epileptic mechanism (ENDOGENOUS AED)

Start date: Sep 1, 2012, End date: Aug 24, 2017,

Epilepsy is a prevalent neurological disorder affecting more than 1 % of all people, with the estimated number of 900,000 children and adolescents suffering from active epilepsy in Europe. Most current drugs targeting this disease have important adverse side-effects. An ideal drug would, however, potentiate the endogenous anti-seizure mechanisms that keep most humans epilepsy-free.To date, these n ...
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 2

 FINISHED 

"From Brain Gene Transfer Towards Gene Therapy: Pharmacological Assessment of AAV, CAV and LVV" (BRAINVECTORS)

Start date: Nov 1, 2012, End date: Oct 31, 2016,

"BRAINVECTORS aims devising new gene therapy(GT)-based treatments for Parkinson’s and other neurodegenerative diseases, in substitution of current systemic treatments, by delivering neurotrophic factors (GDNF) into the CNS with new vectors derived from adeno-associated (AAV), canine adenoviruses (CAV) and lentiviruses (LV) with inducible gene expression.Although AAV, CAV and LVV are considered acc ...
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 12

 FINISHED 

Role of DNA methylation in the regulation of lincRNAs in Hematological Malignancies (LincMHeM)

Start date: Sep 1, 2013, End date: Aug 31, 2016,

"Traditionally, cancer researchers have focused their best efforts on studying the genetic alterations affecting the coding genes. Subsequently, it was observed that in addition to genetic alterations, epigenetic alterations affecting coding genes play an important role in tumor development. In the last decade, largely due to the ability to sequence the human genome and the observation that much o ...
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 1

 FINISHED 

Interspecies endotheliarization for organ xenotransplantation (INTEREXT)

Start date: Apr 1, 2014, End date: Apr 12, 2016,

Organ transplantation is an efficient approach or remedying end-life diseases that cannot be treated by other methods. Nevertheless, the available organs do not cover the clinical demand. As an alternative to the transplantation human organs, the xenotransplantation of animals’ organs has been proposed. Unfortunately, despite the big effort of the last decades, organs are severely rejected upon xe ...
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 1

 FINISHED 

NEW ADVANCED VACCINES IN CHRONIC HEPATITIS B (NAVICHEB)

Start date: Apr 1, 2011, End date: Mar 31, 2015,

"Despite effective vaccines, hepatitis B virus (HBV) infection remains a major health problem with 2 billion people infected worldwide. Among them, 350 million are chronically infected, a major risk factor for development of hepatocellular carcinoma (HCC). A new and efficient treatment against chronic infection and HCC is strongly needed, and therefore it is important to understand HBV replication ...
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 1

 FINISHED 

The roles of juvenile NMDA receptors in synapse maturation and elimination and their association with cognition (NMDAR-synprun)

Start date: Mar 1, 2013, End date: Feb 28, 2015,

The aim of the project is to understand how the NMDA receptor subunit NR3A is involved in selective synapse elimination (“pruning”) during development and how the abnormal expression of NR3A found in mental disorders such as Schizophrenia, Alzheimer´s disease and Huntington correlates with the reduction of functional synapses and deficits in the cognitive function. Importantly, the Host lab has al ...
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 1

 FINISHED 

Mediterranean Verandahways (ECO-VALLE)

Start date: Sep 1, 2002, End date: Aug 31, 2005,

Background Madrid is a fast-growing city, with population growth resulting largely from immigration into the urban area. The city is expanding in particular to the south-east, with the development of the Vallecas area. At the time of project conception, 26,000 new apartment dwellings were being built, ranging from small units to larger, upmarket developme ...
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 3

 FINISHED 

Dietitians ensuring education, teaching and professional quality

Start date: Oct 1, 2010,

The Thematic Network "Dietitians Improving Education and Training Standards" (2006-09) successfully published first cycle competences, influenced education policy change and increased web-based and innovative communication between higher education (HE) and the dietetic profession. But to effectively contribute to policies and practices averting the European health crisis (WHO, 2007) and poor nutri ...
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