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Mucus Permeating Nanoparticulate Drug Delivery Systems (ALEXANDER)

Start date: Apr 1, 2012, End date: Mar 31, 2016,

The objective of the ALEXANDER project is the identification of novel strategies (e.g., proteolytic enzyme strategy, thiomer strategy, zeta potential changing systems, SNEDDS strategy) and the optimization of existing strategies (e.g., disulfide breaking strategy and slippery surface strategy) for the efficient transport of nanocarriers through the mucus gel layer (e.g., intestinal, nasal, ocular, ...
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"Worldwide, there is a strong trend towards highly efficient, low (preferably zero) emission vehicles, i.e. electrical vehicles. In order to facilitate the transition from conventional fuel-driven vehicles towards electrically driven vehicles, there is a short(er) term need for advanced plug-in hybrids and electrical vehicles with range extenders. For this purpose, highly efficient, compact, clean ...
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