8 European Projects Found
Searched on 125080 European Projects
FINISHED
Generation of the CanPath prototype - a platform for predictive cancer pathway modeling (CanPathPro)
Start date: Mar 1, 2016, End date: Feb 28, 2021,
Recent developments in omics technologies demand implementation of systems biology approaches to facilitate analysis and interpretation of the generated complex datasets.This is essential for biotechnological as well as preclinical and clinical applications. In comparison to previous approaches, most cancer relevant studies are confined to pattern recognition or at best modelling of single pathway ...
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9
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Repair of tissue and organ damage in refractory chronic graft versus host disease after hematopoietic stem cell transplantation by the infusion of purified allogeneic donor regulatory T lymphocytes (TREGeneration)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
Our proposal encompasses parallel clinical trials addressing the feasibility and the effectiveness of donor-derived regulatory T cells (Treg) as a therapeutic agent in the treatment and prevention of tissue and organ damage resulting from graft versus host disease (GVHD) after hematopoietic stem cell transplantation (HSCT).We propose a collaborative clinical study in which Treg therapy for GHVD is ...
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8
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Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
...markers in clinical trials, 5 SMEs with unique technologies for CTC isolation (Vycap, Leukocare, Gilupi) or for creation of databases, analysis of complex molecular information and data management (Alacris, TATAA) and two non-profit organizations (IBBL, a Biobank with extensive experience in the validation and execution of plasma assays; EORTC, the European organization that aims to develop, condu ...
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34
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Simulation Modeling of coronary ARTery disease: a tool for clinical decision support (SMARTool)
Start date: Jan 1, 2016, End date: Jun 30, 2019,
SMARTool aims at developing a platform based on cloud technology, for the management of patients with coronary artery disease (CAD) by standardizing and integrating heterogeneous health data, including those from key enabling technologies. The platform includes existing multiscale and multilevel ARTreat (FP7-224297) models of coronary plaque progression based on non-invasive coronary CT angiograph ...
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11
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PROtein SEQuencing using Optical single molecule real-time detection (PROSEQO)
Start date: Mar 1, 2016, End date: Feb 28, 2019,
The advent of analytical techniques with extremely low limits of detection has led to dramatic progresses mostly in the field of nucleic acids sequencing. Despite the advent of the next generation sequencing platforms, the current genome sequencing task remains formidable, and revolutionary advances in DNA sequencing technology are still demanded. Nevertheless, the primary actors in virtually all ...
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5
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Systems biology for the functional validation of genetic determinants of skeletal diseases (SYBIL)
Start date: Oct 1, 2013, End date: Sep 30, 2018,
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and transnational scientists, systems biologists, disease modellers, leading SMEs and industrialists that will perform in-depth char ...
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19
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OncoTrack - Methods for systematic next generation oncology biomarker development (ONCOTRACK)
Start date: Jan 1, 2011, End date: Dec 31, 2016,
We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
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22
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IT Future of Medicine (ITFoM)
Start date: May 1, 2011, End date: Apr 30, 2012,
Data-rich, individualised medicine poses unprecedented challenges for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, ...
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