5 European Projects Found
Searched on 125080 European Projects
FINISHED
Systems Biology of Colorectal Cancer (SYSCOL)
Start date: Jan 1, 2011, End date: Dec 31, 2015,
Colorectal cancer (CRC) is one of the most common cancers in both males and females, and it is perhaps the best understood of all epithelial tumors in terms of its molecular origin. Yet, despite large amount of work that has concentrated on understanding of colon tumorigenesis, we still do not know the full complement of molecular lesions that are individually necessary – and together sufficient – ...
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11
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Euro-BioImaging - Research infrastructure for imaging technologies in biological and biomedical sciences (Euro-BioImaging)
Start date: Dec 1, 2010, End date: May 31, 2014,
Euro-BioImaging brings together imaging technologies stretching from basic biological imaging with advanced light microscopy, in vivo molecular imaging of single cells to animal models up to the clinical and epidemiological level of medical imaging of humans and populations. Euro-BioImaging, in close consultation with its stakeholders, will address the imaging requirements of both biological and m ...
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44
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INtegrated HEart Research In TrANslational genetics of dilated Cardiomyopathies in Europe (INHERITANCE)
Start date: Jan 1, 2010, End date: Dec 31, 2013,
"Inherited dilated cardiomyopathies (DCM) are monogenic disorders caused by mutations in more than 30 genes, characterised by substantial phenotype heterogeneity. DCM affects 1:2.500 individuals and is the major cause of heart transplantation and death for non-ischaemic heart failure in adolescents and young adults. Currently, less than 1% of patients with familial DCM are genotyped in Europe. The ...
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11
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Prediction of bladder cancer disease course using risk scores that combine molecular and clinical risk factors (UROMOL)
Start date: Feb 1, 2008, End date: Jul 31, 2013,
"Bladder cancer is a recurrent and very prevalent cancer and it generates the highest cost per patient in Europe. New genomic methods have allowed identifying new markers with potential clinical application. However, due to the use of single-marker assays and poor study design, none of these markers has made it to the clinic. FGFR3 and PIK3CA mutations, expression profiles, and microsatellite alte ...
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8
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Genomic Instability in Cancer and Precancer (GENICA)
Start date: Jan 1, 2008, End date: Dec 31, 2010,
"Genomic instability is a characteristic of practically all human cancers. Recent results generated by members of this Consortium suggest that signs of genomic instability are evident from the very beginning of human cancer development, even in precancerous lesions. In these early lesions, the genomic instability affects primarily specific genomic loci, called common fragile sites. Because common ...
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