Search for European Projects

24 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Training network providing cutting-EDGE knowlEDGE on Herpes Virology and Immunology (EDGE)

Start date: May 1, 2016, End date: Apr 30, 2020,

Herpesviruses are widely spread, and cause life-long infections. Most individuals carry multiple herpesviruses, which can cause severe diseases, especially in children, immunocompromised individuals, and elderly. There are currently no safe vaccines against herpesvirus infections and current treatments are not satisfactory. With new insights into the molecular basis for diseases caused by immunode ...
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 9

 FINISHED 

DOLORisk: Understanding risk factors and determinants for neuropathic pain (DOLORisk)

Start date: Jul 1, 2015, End date: Jun 30, 2019,

Neuropathic pain (NP) is common (population prevalence of 7-8%) and will present a rising health burden in the future. NP results in significant morbidity, reduces quality of life and has a major deleterious impact on health in aging. The reason why some subjects develop neuropathic pain and others do not following the same injury is not known. The exact nature of risk factors for NP and their int ...
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 14

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Adverse Immune Signatures and their Prevention in Corneal Transplantation (VISICORT)

Start date: Apr 1, 2014, End date: Mar 31, 2019,

"Immune system response is the most complex barrier to long-term success of tissue transplants/implants from allogeneic and bio-artificial sources. While newly developed tissue transplant procedures are not yet performed frequently enough for robust analysis of adverse immune responses in humans, corneal transplantation (CT) is a well-established allogeneic tissue transplant with >100,000 full- an ...
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 12

 FINISHED 

Accelerated Development of Vaccine benefit-risk Collaboration in Europe (ADVANCE)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

Aim: The ADVANCE vision is focused on Timely and Best Evidence on Vaccine Effects. Our mission is to establish a best practice framework to rapidly provide robust data on vaccine benefits and risks to support accelerated decision-making.Approach: To achieve this vision through a public-private partnership, ADVANCE partners 1. establish common grounds and rules for collaboration between public and ...
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 30

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European Medical Information Framework (EMIF)

Start date: Jan 1, 2013, End date: Dec 31, 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

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Efficacy and safety of MRI-based thrombolysis in wake-up stroke: a randomised, double-blind, placebo-controlled trial (WAKE-UP)

Start date: Dec 1, 2011, End date: Nov 30, 2017,

WAKE-UP is an investigator-initiated, multicentre, randomised, double-blind, placebo-controlled trial designed to test efficacy and safety of MRI-based intravenous thrombolysis in patients with wake-up stroke. Every year 1.5 million patients suffer a stroke in the EU. Up to 20% of stroke patients wake up with stroke symptoms. Currently these patients are excluded from thrombolysis which is the onl ...
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 13

 FINISHED 

Food-based solutions for Optimal vitamin D Nutrition and health through the life cycle (ODIN)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

Vitamin D deficiency has significant implications for human health and impacts on healthy growth and development and successful aging. Fundamental knowledge gaps are barriers to implementing a safe and effective public health strategy to prevent vitamin D deficiency and optimize status. ODIN will provide the evidence to prevent vitamin D deficiency in Europe and improve nutrition and public health ...
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 32

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"Retinal Vascular Modeling, Measurement and Diagnosis" (REVAMMAD)

Start date: Apr 1, 2013, End date: Mar 31, 2017,

"The REtinal VAscular Modeling, Measurement And Diagnosis (REVAMMAD) project will train a new generation of scientists able to effectively translate the latest vascular modeling theory and computerized image analysis techniques into effective interventions for some of the most important chronic medic conditions afflicting the EU, including hypertension and diabetes. It will particularly ensure tha ...
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 10

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Systems Biology of Colorectal Cancer (SYSCOL)

Start date: Jan 1, 2011, End date: Dec 31, 2015,

Colorectal cancer (CRC) is one of the most common cancers in both males and females, and it is perhaps the best understood of all epithelial tumors in terms of its molecular origin. Yet, despite large amount of work that has concentrated on understanding of colon tumorigenesis, we still do not know the full complement of molecular lesions that are individually necessary – and together sufficient – ...
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 11

 FINISHED 

CAncer Risk and INsulin analoGues (CARING)

Start date: Nov 1, 2011, End date: Oct 31, 2015,

"Several studies have linked the use of insulins to the risk of cancer, and it is certainly plausible that as a growth factor, exposure to administered insulin could stimulate neoplastic growth. However, the meta-analyses of randomized clinical trials comparing different insulin analogues were too small to quantify the risks, especially the proportion of patients that were followed for more than ...
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 8

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Understanding chronic pain and improving its treatment (EUROPAIN)

Start date: Oct 1, 2009, End date: Sep 30, 2015,

We will establish an international team of leading researchers and clinicians (EuroPain) to undertake multidisciplinary translational research which will: 1) increase the understanding of chronic pain mechanisms; 2)facilitate the development of novel analgesic drugs; and 3) improve the treatment of chronic pain patients.Nineteen researchers drawn from the London Pain Consortium, the Danish Pain Re ...
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 29

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Union of Light-Ion Centres in Europe (ULICE)

Start date: Sep 1, 2009, End date: Aug 31, 2014,

ULICE is a 4-year project set up by 20 leading European research organisations, including 2 leading European industrial partners (Siemens and IBA), to respond to the need for greater access to hadron therapy facilities for particle therapy research. Project coordinator is the Italian Research Infrastructure Facility CNAO (Milan). Both existing European Hadron Research Facilities in Heidelberg and ...
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 20

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Metastatic tumours facilitated by hypoxic tumour micro-environments (METOXIA)

Start date: Feb 1, 2009, End date: Jul 31, 2014,

"Recent research suggests that the hypoxic micro-environment of tumours is one of the major drivers of metastatic spread of cancer. Furthermore, hypoxic tumour micro-environments may result in treatment resistance of cancer cells, therefore causing a double effect of reducing the potential of a successful treatment of the cancer patient. This project seeks to clarify the roles and functions of the ...
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 21

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Euro-BioImaging - Research infrastructure for imaging technologies in biological and biomedical sciences (Euro-BioImaging)

Start date: Dec 1, 2010, End date: May 31, 2014,

Euro-BioImaging brings together imaging technologies stretching from basic biological imaging with advanced light microscopy, in vivo molecular imaging of single cells to animal models up to the clinical and epidemiological level of medical imaging of humans and populations. Euro-BioImaging, in close consultation with its stakeholders, will address the imaging requirements of both biological and m ...
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 44

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Natural products from marine fungi for the treatment of cancer (MARINE FUNGI)

Start date: May 1, 2011, End date: Apr 30, 2014,

The aim of MARINE FUNGI is the demonstration of sustainable exploitation of marine natural resources providing appropriate culture conditions for the underutilised group of marine fungi, thus enabling efficient production of marine natural products in the laboratory and also in large scale cultures, avoiding harm to the natural environment. The focus of MARINE FUNGI are new anti-cancer compounds T ...
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 14

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INtegrated HEart Research In TrANslational genetics of dilated Cardiomyopathies in Europe (INHERITANCE)

Start date: Jan 1, 2010, End date: Dec 31, 2013,

"Inherited dilated cardiomyopathies (DCM) are monogenic disorders caused by mutations in more than 30 genes, characterised by substantial phenotype heterogeneity. DCM affects 1:2.500 individuals and is the major cause of heart transplantation and death for non-ischaemic heart failure in adolescents and young adults. Currently, less than 1% of patients with familial DCM are genotyped in Europe. The ...
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 11

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Climate change, Environmental contaminants and Reproductive health (CLEAR)

Start date: May 1, 2009, End date: Oct 31, 2013,

The research project investigates the possible impact of global climate change on reproductive health in one Arctic and two European populations. The key questions to be addressed are, firstly, how may climate change influence human exposure to widespread environmental contaminants and, secondly, how may contaminants impact occurrence of reproductive disorders as sensitive indicators of health? To ...
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 8

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Prediction of bladder cancer disease course using risk scores that combine molecular and clinical risk factors (UROMOL)

Start date: Feb 1, 2008, End date: Jul 31, 2013,

"Bladder cancer is a recurrent and very prevalent cancer and it generates the highest cost per patient in Europe. New genomic methods have allowed identifying new markers with potential clinical application. However, due to the use of single-marker assays and poor study design, none of these markers has made it to the clinic. FGFR3 and PIK3CA mutations, expression profiles, and microsatellite alte ...
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 8

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Arrhythmogenic potential of drugs (ARITMO)

Start date: Jan 1, 2010, End date: Jun 30, 2013,

The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
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 21

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Exploring and understanding adverse drug reactions by integrative mining of clinical records and biomedical knowledge (EU-ADR)

Start date: Feb 1, 2008, End date: Jan 31, 2012,

Serious adverse effects resulting from the treatment with thalidomide prompted modern drug legislation more than 40 years ago. Post-marketing spontaneous reporting systems for suspected adverse drug reactions (ADRs) have been a cornerstone to detect safety signals in pharmacovigilance. It has become evident that adverse effects of drugs may be detected too late, when millions of persons have alrea ...
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 15

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Sensory and Biomechanical Markers in Diabetic Neuropathy of the Gut. Basic Investigations and New Approaches for Treatment (DIAMARK)

Start date: Nov 1, 2008, End date: Oct 31, 2011,

"DIAMARK is focused on analysing the pathophysiology of diabetic neuropathy and to determine better biomarkers of the complications and approaches for intervention. Due to lack of standardisation, there are no accepted biomarkers to evaluate the neuropathy and its involvement in the GI tract. Diabetes mellitus (DM) is one of the most common endocrine disorders affecting almost 6% (app. 246 million ...
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 6

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Early and late health risks to normal/healthy tissues from the use of existing and emerging techniques for radiation therapy (ALLEGRO)

Start date: Feb 1, 2009, End date: Mar 31, 2011,

Curative cancer treatment with radiation seeks to optimise the magnitude of the radiation dose to the treatment volume while restricting the dose to normal healthy tissue. With an increasing population of surviving cancer patients treated with radiation therapy, the harmful effects of the radiation to normal tissue are becoming more evident. The ALLEGRO project will address the many aspects of n ...
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 13

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ENVIRONMENTAL HEALTH RISKS IN EUROPEAN BIRTH COHORTS (ENRIECO)

Start date: Mar 1, 2009, End date: Feb 28, 2011,

"The overall aim of ENRIECO is to advance our knowledge on specific environment and health causal relationships in pregnancy and birth cohorts by providing support to exploitation of the wealth of data generated by past or ongoing studies funded by the EC and national programmes. Specific objectives are to make inventories of birth cohorts, assure quality and interoperability of exposure, health ...
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 9

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Genomic Instability in Cancer and Precancer (GENICA)

Start date: Jan 1, 2008, End date: Dec 31, 2010,

"Genomic instability is a characteristic of practically all human cancers. Recent results generated by members of this Consortium suggest that signs of genomic instability are evident from the very beginning of human cancer development, even in precancerous lesions. In these early lesions, the genomic instability affects primarily specific genomic loci, called common fragile sites. Because common ...
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 11