SATORI is a 45-month project, comprising 17 partners from 13 countries, including an intergovernmental organisation, the aim of which is to improve respect of ethics principles and laws in research and innovation, and to make sure that they are adequately adapted to the evolution of technologies and societal concerns. The partners will develop an ethics assessment framework based on thorough analysis, commonly accepted ethical principles, participatory processes and engagement with stakeholders, including the public, in Europe and beyond.The project comprises 12 work packages, starting with a systematized inventory of current practices and principles in ethics assessment. WP2 reviews existing projects and identifies stakeholders. WP3 investigates the impact of globalization and the extent to which research is conducted outside Europe to profit from more flexible frameworks. In WP4, the partners outline an ethical assessment framework and create a roadmap for a fully developed framework. WP5 concerns the cost-effectiveness and risk-benefit of ethics assessment. WP6 address other impacts and gathers stakeholder views on those impacts. The partners will study the prospects for standardizing the framework in WP7. In WP8, the partners will develop a strategy for sustainability of the SATORI network. In WP9, which runs throughout the project, the partners will monitor policy developments and other initiatives at the EU, MS and local levels which merit ethical assessment and alert our network accordingly. The partners have devised a multi-pronged communications strategy to interact with stakeholders in WP10. WP11 is project management. In WP12, the partners have created an independent evaluation of and reflection upon the project, which will enable any necessary remedial actions to enhance it. SATORI’s experienced partners bring complementary perspectives and knowledge from academia, industry, research institutes, science academies, journalism and other sectors.