The Danish EU presidency conference ’Science in Dialogue’ will bring together policy makers, research institutions, businesses, professional science communicators and NGOs to discuss and reflect on the relationship between science and society. The conference will take place in the city of Odense, Denmark, from April 23 to April 25 2012.A strenghtened dialogue and interaction between science and society is vital if science is to deliver on the solutions needed for addressing the major societal challenges. A mutual responsiveness between researchers, innovators and society at large must be an underlying mindset and precondition Horizon 2020 as well as for other future European frameworks.The overall objectives of the presidency conference are to: Offer a platform for stakeholders from Europe and abroad to discuss and reflect on the interaction and dialogue between science and society; Provide input on aspects of a European model for Responsible Research and Innovation (RRI); Provide input to future instruments for research funding; Promote a basis for the successful solution of the grand challenges in Horizon 2020.The conference will present high-level speakers and part of the programme will be dedicated to workshops based on participatory methodology during which the participants will be urged to exchange and discuss cases and best practices to the participants. The conference will thereby also seek to inspire and to support the formation of a European network on the subject matter.The conference will be organised by the Danish Agency for Science, Technology and Innovation under the Danish Ministry for Science, Innovation and Higher Education.