The overall aim of the joint research programme is to enhance the research activities in study of the risk factors of work-related diseases with special emphasis paid to cardiovascular and musculoskeletal system. Cardiovascular and musculoskeletal diseases, are the main health problem both in western and developing countries Among occupational and environmental risk factors the important role plays work-related stress. It seems that influence of stress on cardiovascular and musculoskeletal systems could have common mechanism of pathogenicity, via neurovegetative disturbances, especially stimulation of the sympathetic and depression of the parasympathetic nervous system. The problem of work-related stress and its health consequences is particular important in countries in transitions as for example Russia or Ukraine, where changing in nature of work and globalisation cause that people have to deal with increasing work-related stress. This problem is poorly recognize. The transfer of knowledge will be implemented by various activities: training programmes, including a series of researches’ visits to the Work Physiology and Ergonomics Department of Nofer Institute of Occupational Medicine in Lodz, Poland and visits our staff at partners institutions from Norway, Denmark, Great Britan, Sweden, Hungary, Italy, Russia and Ukraine. Moreover networking activities and pilot studies are planned. The transfer of knowledge and know-how regarding risk factors of work related diseases will increase the potential for designing joint research projects and will be helpful in preparing proposals within FP7. Research activities within our project will contribute to reducing the CVD and MSD epidemic throughout: better management of occupational risk factors, use of the available more technological advances for improve working conditions, methodological advances in cardiovascular and musculoskeletal system evaluation in workers exposed to occupational risk factors.