NEWCOM# is a Network of Excellence (NoE) proposal submitted in response to challenge FP7-ICT-2011-8 1.1, "Future Networks". A group of 14 partners in 14 different countries (12 of which come from the former FP7 NoE NEWCOM++) decided to capitalize on the high degree of integration in research they already at-tained to build an NoE with the following objectives: i) to produce medium to long term results in the area of design and performance evaluation of wireless networks; ii) to strengthen the integration of partners' re-search activities and agendas, both at the theoretical and experimental levels; iii) to foster Industry-academia cooperation, dissemination, and liaison by making academic research closer to industrial needs and interests; iv) to provide a unique training environment for a new generation of researchers in both theo-retical and experimental research; v) to contribute to the long-term sustainability of the NoE by creating a permanent environment for cooperative research.In a "Theoretical Research" track, the NEWCOM# researchers will pursue long-term, interdisciplinary re-search on the most advanced aspects of wireless communications like Finding the Ultimate Limits of Com-munication Networks, Opportunistic and Cooperative Communications, Energy- and Bandwidth-Efficient Communications and Networking. A second track will be devoted to the "EUropean lab of Wireless commu-nications for the future INternet", a federation of three sites in three European Countries that will host re-searchers working on a few general themes like Radio Interfaces, Internet of Things, and Flexible Communi-cation Terminals. The third track will have a number of initiatives to foster excellence like the creation of seasonal schools, a series of publication on journals and books, and an action directed towards strengthen-ing relations with European companies, which will participate to the NoE as "Affiliate Partners", through a number of in-company dissemination events.