Hydro-meteorological monitoring and flood forecasting are indispensable for preventing and mitigating hydrological hazards, such as floods, and for ensuring civil protection. Implementing a plan that acknowledges the principles of sustainability to combat floods requires further activities regarding agriculture, forestry and land-use management in flood risk areas. As most river catchments areas belong to more than one country or region, methodologies have to be developed within a transnational and a transregional context that go beyond local concepts. The project regions of FLOODMED are characterised by an increase in the number of people and economic assets located in flood risk zones, while at the same time the areas lack an integrated flood management plan. The project aims at developing effective flood risk management programs, incorporating the basic elements of flood prevention, protection, preparedness, emergency response and recovery. FLOODMED brings together scientists and public servants who will develop a scalable system of operational tools to support integrated water and sustainable flood risk management. Expected Results: In the FLOODMED project transnational methodologies and models will be developed and implemented for flood estimation and forecasting for gauged and ungauged sites, resulting in the proposal of flood mitigation measures and real-time warning systems. The efficacy of different best management practices, structural and non-structural, will be examined in relation to flood prevention and low impact development. Upon project completion, local authorities will have at their disposal, and will be trained to use, a state-of-the-art, viable, integrated system for flood estimation and mitigation, which will constitute a solid basis for decision-making in the field of spatial planning.