"The proposed project will develop a novel programmable ultrathin insulating sheet wrapped carbon nanotube nanowire with DNA recognition ability. The proposed work will for the first time create SWCNT insulated by ultrathin insulating layer. ssDNA recognition element will be attached to the coated/insulated SWCNT. Since DNA is one of the most ""programmable"" molecules, such dual-type of ultrathin layer insulated SWCNT-DNA assembly is unique and will have profound effect on development of nanoelectronic (molectronic) devices, nanobiosensors and on whole area of material science. The understanding of experimental variables as well as electronic/insulation characteristic of assembled programmable SWCNT-DNA will have important effect for proposed project, but it will also have dramatic influence on all field of CNT based nanobiomaterials and nanoelectonic devices. In view of the availability of various carbon nanotubes of different structures and DNA strands of different base sequences, the work proposed will represent an important advance in constructing many multiple carbon nanotube programmable self-assembled structures for multifunctional material, sensing and nanoelectronic device applications."