Currently universities of economics and business in Kazakhstan, Kyrgyzstan and Uzbekistan have to master a series of challenges. They have• to demonstrate that they are reliable providers of good quality higher education by providing graduates with competencies required to evolve their professionality and to develop capacity for the labor market• to enrich the qualification-portfolio of HEI-teachers by improving their teaching qualifications• to complement and contribute to the co-creation of knowledge and to the knowledge exchange between universities and enterprises in innovative settings• to develop their students competencies and attitudes to enable them to act as innovative and responsible members of the society.In this joint project "Teaching Competencies in Economics and Business" will serve universities of economics and business as catalyzer to master these challenges. To support the development of excellence in this field a “Central Asian Center for Teaching, Learning and Entrepreneurship - CACTLE” will be implemented in the innovative form of an international acting virtual expert network with a sustainable perspective.The CACTLE will be dedicated • to qualify and certify HEI-teachers in modern Teaching Competencies in Economics and Business for the target groups: students, employees of private companies/public institutions and entrepreneurs.• to offer a course program and in class and long-distance training material for further training courses for enterprises/institutions to link the universities to business and industry, using specific modalities of teaching and learning patterns.• to develop a core-curriculum and teaching and learning material for an accredited elective “Entrepreneurship and Business development” at all participating universities.In the long run the CACTLE will have a sustainable impact on human capacity building of Central Asian countries and will act as an international service network to foster the knowledge triangle.